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Last $4.13 USD
Change Today -0.08 / -1.90%
Volume 2.7M
ARNA On Other Exchanges
As of 5:20 PM 05/6/15 All times are local (Market data is delayed by at least 15 minutes).

arena pharmaceuticals inc (ARNA) Snapshot

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Day High
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52 Week High
05/9/14 - $7.22
52 Week Low
10/13/14 - $3.26
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arena pharmaceuticals inc (ARNA) Details

Arena Pharmaceuticals, Inc., a biopharmaceutical company, discovers, develops, and commercializes novel drugs that target G protein-coupled receptors. The company offers BELVIQ, a drug used to treat chronic weight management in adults. It is also developing a portfolio of programs in various therapeutic areas, including cardiovascular, central nervous system, and metabolic diseases. Its products under development include Ralinepag, an agonist of the prostacyclin receptor intended for the treatment of vascular diseases, including potentially pulmonary arterial hypertension that is in Phase II clinical trials. The company’s products under development also comprise APD334, an modulator of the sphingosine 1-phosphate subtype 1 receptor for the treatment of a various autoimmune diseases, which has completed Phase I single-ascending dose trials; APD371, an agonist of the cannabinoid receptor 2 that is in Phase I clinical trials intended for the treatment of pain and fibrotic diseases; and Temanogrel, an inverse agonist of the serotonin 2A receptor intended for the treatment of thrombotic diseases, which has completed single- and multiple-ascending dose Phase I clinical trials. In addition it manufactures drug products under a toll manufacturing agreement for Siegfried AG. The company was founded in 1997 and is based in San Diego, California.

325 Employees
Last Reported Date: 03/2/15
Founded in 1997

arena pharmaceuticals inc (ARNA) Top Compensated Officers

Co-Founder, Chairman, Chief Executive Officer...
Total Annual Compensation: $746.8K
Co-Founder, Chief Scientific Officer, Executi...
Total Annual Compensation: $441.0K
Chief Financial Officer, Principal Accounting...
Total Annual Compensation: $378.0K
Executive Vice President, General Counsel and...
Total Annual Compensation: $415.0K
Chief Medical Officer and Senior Vice Preside...
Total Annual Compensation: $394.0K
Compensation as of Fiscal Year 2014.

arena pharmaceuticals inc (ARNA) Key Developments

Arena Pharmaceuticals Reports Favorable Results from Phase 1 Single-Ascending Dose Clinical Trial of APD371

Arena Pharmaceuticals, Inc. announced favorable results from a Phase 1 single-ascending dose clinical trial of APD371, a highly selective and potent agonist of the cannabinoid 2 (CB2) receptor currently in development for the treatment of pain and potentially fibrotic diseases. The randomized, double-blind and placebo-controlled Phase 1 clinical trial enrolled 56 healthy adults to evaluate the safety, tolerability and pharmacokinetics of single-ascending doses of APD371. Dose responsive exposure was observed over the explored dose range of 10-400 mg with good tolerability at all doses administered.

Eisai Inc. and Arena Pharmaceuticals, Inc. Complete Registrational Trials of an Extended Release Formulation of Lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ. If approved, the extended release formulation is expected to be marketed as BELVIQ XR, which is the brand name conditionally approved by the FDA. Each of the two randomized, crossover trials evaluated the safety, tolerability, pharmacokinetics and bioavailability of an extended release formulation of lorcaserin in 36 healthy adult subjects. Patients in each trial were divided into two treatment groups and received both doses in a two-way crossover sequence. Patients in the first study were dosed under fasted conditions either 10 mg twice-daily immediate release or 20 mg once-daily extended release. Patients in the second study were dosed either 20 mg QD extended release in the fasted state or 20 mg QD extended release in the fed state. The most common treatment-emergent adverse events were similar to those seen in the Phase 3 clinical trials of BELVIQ, and included mild or moderate headache, constipation, dizziness and nausea. There were no discontinuations for adverse events, and no serious adverse events were observed. Lorcaserin extended release formulation is investigational and not approved by any regulatory agency.

Arena Pharmaceuticals, Inc. Presents at Needham & Company's 14th Annual Healthcare Conference, Apr-15-2015 12:50 PM

Arena Pharmaceuticals, Inc. Presents at Needham & Company's 14th Annual Healthcare Conference, Apr-15-2015 12:50 PM. Venue: Westin Grand Central Hotel, New York, New York, United States.


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