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Last 84.00 TWD
Change Today +0.20 / 0.24%
Volume 591.1K
As of 2:31 AM 09/3/15 All times are local (Market data is delayed by at least 15 minutes).

medigen biotechnology corp (3176) Snapshot

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09/11/14 - 204.00
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08/25/15 - 73.30
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medigen biotechnology corp (3176) Details

Medigen Biotechnology Corp. focuses on the development of therapies for liver diseases and cancers in Taiwan. The company is developing PI-88 (MUPAFOSTAT), which is in Phase III clinical trials for the treatment of liver cancer; PI-88 (MUPARFOSTAT) that is in Phase II clinical trials for use as an adjuvant therapy for HCC after curative surgery, as well as in Phase III trials for the adjuvant treatment of patients with hepatitis virus related hepatocellular carcinoma after surgical resection; and OBP-301, which is in Phase I/II clinical trials to treat cancer. It also develops human native mAbs for therapeutic applications related to infectious diseases; two cell-based vaccine products; and nucleic acid testing products for diagnostics in pathogens, personalized medicine, and genetic diseases, as well as provides third-party testing services. In addition, the company offers pharmaceuticals for infectious diseases and contraceptives; health products, such as functional nutrition milk powder and vitamin C tablets; and dermatologic agents and eye care products. Medigen Biotechnology Corp. was founded in 1999 and is headquartered in Taipei City, Taiwan.

Founded in 1999

medigen biotechnology corp (3176) Top Compensated Officers

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medigen biotechnology corp (3176) Key Developments

Medigen Biotechnology Corp., Annual General Meeting, Jun 22, 2015

Medigen Biotechnology Corp., Annual General Meeting, Jun 22, 2015.

Medigen Biotechnology Corp. Provides Additional Information on the Results of the Interim Analysis for the Phase III Patron Clinical Trial for PI-88

Medigen Biotechnology Corp. has provided additional information on the results of the interim analysis for the Phase III PATRON clinical trial for PI-88. The PATRON trial is a fully recruited randomised, placebo-controlled Phase III trial being conducted in Taiwan, South Korea, China and Hong Kong to confirm the safety and efficacy of PI-88 in the adjuvant treatment of hepatocellular carcinoma after surgical resection. The results of the interim analysis carried out on the Phase III clinical trial for PI-88 indicated that it did not meet the primary endpoint of Disease Free Survival, and that further analysis of the data will be conducted by an independent medical imaging company in the US, BioClinica. It is now expected that this analysis by BioClinica of the patients' CT and magnetic resonance data will be conducted by the end of the year, and will be an important reference for the efficacy of PI-88. Further, Medigen is continuing PI-88's Phase III PATRON clinical trial in 25 clinical centres. Medigen is expecting to complete the final analysis on the total targeted recurrent 218 patients in 2015, to ensure that a final analysis can be conducted on PI-88's compliance with various endpoints. Medigen has provided further information on the differences between this interim analysis and the final analysis expected in 2015. The efficacy endpoints for the Phase III PATRON clinical trial for PI-88 include: 1. Disease Free Survival; 2. Time To Recurrence; 3. Tumour Recurrence Rate; and 4. Overall Survival. The interim analysis mainly analysed the primary endpoint of Disease Free Survival, whereas the final analysis will analyse all of the efficacy endpoints to determine the complete safety and efficacy profile of PI-88. Both the interim and final analysis use the two-tailed P-value to determine the statistical difference between the treatment and placebo groups. The smaller the P-value, the more significant the difference, or the higher the efficacy. Generally, there is a significant difference when the P-value is lower than 0.05. In line with PI-88's Phase III trial protocol, the interim analysis was only based on 60% of the available data, and therefore the P-value was set very low at 0.01806, to demonstrate whether PI-88 meets the statistical significant difference. The final analysis will be conducted on the data from the total targeted recurrent 218 patients, and as such the statistical significant difference has been set at a P-value of 0.04148.

Medigen Presents at 2014 Asia Biotech Invest Conference, Jun-05-2014 10:20 AM

Medigen Presents at 2014 Asia Biotech Invest Conference, Jun-05-2014 10:20 AM. Venue: Sheraton Hong Kong Hotel & Towers, 20 Nathan Road, Kowloon, Hong Kong. Speakers: David Ma, Business Development Director.


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