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August 01, 2015 2:24 PM ET

Biotechnology

Company Overview of AbGenomics International, Inc.

Company Overview

AbGenomics International, Inc., a biopharmaceutical company, focuses on the discovery and development of antibody therapeutics for the treatment of cancer and immune related inflammatory diseases. It offers AbGn-168, an immunomodulating investigational therapeutic antibody against CD162 that induces apoptosis of late-stage activated T cells and other immune cells, as well as spare naive, regulatory, and memory T cells; various animal disease models, such as CIA, NOD, and allergy, as well as transplantation rejection/GVHD in murine and DTH in non-human primate; and autoimmune diseases, including rheumatoid arthritis, Crohn's disease, lupus, and psoriasis. The company also provides antibody-7 ...

4984 El Camino Real

Suite 100

Los Altos, CA 94022

United States

Founded in 2000

Phone:

650-988-9912

Fax:

650-988-9913

Key Executives for AbGenomics International, Inc.

Founder, Chairman of the Board and Chief Executive Officer
Director of Operation, Corporate Secretary and Director
Director of IP Management & Quality Assurance
Director of Project & Alliance Managements
Chief Scientific Officer
Compensation as of Fiscal Year 2015.

AbGenomics International, Inc. Key Developments

AbGenomics International Announces Initiation of Phase-Ib/IIa Clinical Trial of Neihulizumab (AbGn-168H) for the Treatment of Steroid Refractory Acute GvHD (aGvHD)

AbGenomics International announced the start of a phase-Ib/IIa clinical trial using the lead compound Neihulizumab (AbGn-168H) to treat steroid refractory acute GvHD (aGvHD). This investigator-initiated trial is sponsored by Stanford University in its bone marrow transplant program. The primary objective of the study is to evaluate the safety and efficacy of AbGn-168H in patients with steroid refractory aGvHD in the post-allogeneic transplantation setting. aGVHD is a major complication of hematopoietic cell transplantation (HCT) that accounts for most non-relapse mortality and limits the use of HCT. Steroid refractory aGVHD carries an especially high mortality of between 60-85%. According to key opinion leaders in this field, a huge unmet medical need of aGvHD needs to be satisfied under the existing therapies. Prior to the aGvHD trial, the proof of clinical efficacy and safety of AbGn-168H, a humanized monoclonal antibody, has been well demonstrated in a randomized, multicenter, double-blind, placebo-controlled phase II trial in patients with moderate-to-severe plaque psoriasis. Most recently, AbGenomics has also initiated an open-label, multi-center phase II study for psoriatic arthritis. The company is dedicated to bring forth this potential game-changing therapeutic candidate for the treatment of various inflammatory diseases.

AbGenomics International, Inc. Presents at 13th Annual BIO Investor Forum, Oct-08-2014 02:30 PM

AbGenomics International, Inc. Presents at 13th Annual BIO Investor Forum, Oct-08-2014 02:30 PM. Venue: The Palace Hotel, San Francisco, CA 94105, United States.

AbGenomics International, Inc. Presents at BioPharm America 2013, Sep-18-2013 03:15 PM

AbGenomics International, Inc. Presents at BioPharm America 2013, Sep-18-2013 03:15 PM. Venue: Westin Boston Waterfront Hotel, Boston, Massachusetts, United States.

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