June 25, 2017 6:08 PM ET

Biotechnology

Company Overview of Octapharma AG

Company Overview

Octapharma AG, a plasma fractionation company, develops, produces, and sells human proteins that are derived from human plasma and human cell-lines in Europe and internationally. It offers haematology products, such as Nuwiq, a human coagulation factor VIII recombinant DNA for the treatment and prophylaxis of bleeding in all age groups with haemophilia A; octanate, a human factor VIII/von Willebrand factor (VWF) concentrate, which is used for the prophylaxis and treatment of bleeding in haemophilia A patients; wilate, a human VWF concentrate to treat von Willebrand disease and haemophilia A patients; and octanine F, a human factor IX concentrate for the prophylaxis and treatment of bleeding ...

Seidenstrasse 2

Lachen,  8853

Switzerland

Founded in 1983

7,094 Employees

Phone:

41 55 4512121

Fax:

41 55 4512110

Key Executives for Octapharma AG

Chairman of Management Board and Chief Executive Officer
Chief Financial Officer and Member of Management Board
Member of Management Board and President of Octapharma Plasma Inc USA
Member of Management Board and President of Octapharma USA INC
Senior Vice President of R&D Plasma - Vienna
Compensation as of Fiscal Year 2016.

Octapharma AG Key Developments

Octapharma Announces Positive Results from Haemophilia A Study

Octapharma AG has announced positive new clinical data in 66 previously treated patients, or PTPs, with severe haemophilia A, or HA, undergoing PK-guided personalized prophylaxis with Nuwiq according to the NuPreviq Approach. The NuPreviq study was initiated in August 2013 with the aim of developing a fully personalized service for HA patients undergoing prophylactic therapy. Octapharma's aim is to improve patient treatment experiences by recognizing that no two HA patients are the same, therefore a 'one size fits all' approach to prophylaxis is not ideal. The NuPreviq study investigated a novel approach, allowing the Nuwiq treatment regimen to be adapted to the specific needs of each individual patient. The NuPreviq Approach measures and profiles each individual patient's pharmacokinetic response to treatment, which then allows the dosing of Nuwiq to be personalized according to the specific circumstances of that patient. The results of the study showed that this personalized prophylaxis approach was very effective at preventing bleeds, while reducing the frequency of dosing and the amount of Nuwiq needed. Over 80% of patients did not experience a spontaneous bleed during the 6 months of personalized prophylaxis with Nuwiq. More than half of the patients received infusions twice a week or less, and dose requirements were reduced by 7%. The study shows that personalized prophylaxis with Nuwiq provides excellent bleeding protection, extension of the dosing interval for most patients, and a reduction in dose. These data further differentiate Nuwiq from other products on the market. The GENA-21 and GENA-21b studies, initiated in August 2013 and March 2015, respectively, are prospective, open-label, multicentre, Phase IIIb studies assessing the safety and efficacy of PK-guided personalized prophylaxis with Nuwiq in previously treated adult patients with severe HA. The studies are each conducted across 29 study locations worldwide. Nuwiq is a naturally long-acting, 4th generation rFVIII protein, produced in a human cell line without chemical modification or fusion with any other protein. Nuwiq is cultured without additives of human or animal origin, is devoid of antigenic non-human protein epitopes and has a high affinity for the von Willebrand coagulation factor. Nuwiq treatment has been assessed in seven completed clinical trials which included 201 PTPs (190 individuals) with severe HA, including 59 children. Nuwiq is approved for use in the treatment and prophylaxis of bleeding across all age groups of PTPs with haemophilia A in the EU, US, Canada, Australia, Latin America and Russia.

The Octapharma Group Announces Earnings Results for the Year 2016

The Octapharma Group announced earnings results for the year 2016. For the year, the company reported sales of €1.6 billion, which represents an increase of €87 million or 5.8% compared with 2015. Octapharma achieved an unprecedented operating income of €383 million.

Octapharma AG Announces Interim Data from Phase III Hemophilia A Study

Octapharma AG has announced interim data from the ongoing Phase III study, NuProtect, in patients with hemophilia A, at the 58th ASH Annual Meeting & Exposition in San Diego, California. The presentation was nominated for inclusion in the 2017 North American Highlights of ASH Roadshow meeting with an abstract published in Blood. The NuProtect Study examines the immunogenicity, efficacy and safety of treatment with human cell-line derived recombinant FVIII (Nuwiq) in previously untreated patients (PUPs) with severe haemophilia A. The presentation focused on immunogenicity of Nuwiq in 66 haemophilia A patients who have received at least 20 days of treatment in the ongoing NuProtect study, with no previous exposure to FVIII concentrates or other blood products. The cumulative incidence (95% confidence interval) of all inhibitors was 20.8% (10.7-31.0); 12.8% (4.5-21.2) for high-titre inhibitors and 8.4% (1.3-15.6) for low-tire inhibitors. These data were reported as part of a pre-planned interim analysis for the NuProtect study, which plans to ultimately evaluate at least 100 PUPs.

Similar Private Companies By Industry

Company Name Region
4bases S.A. Europe
AB2 Bio Ltd. Europe
ADC Products Switzerland SARL Europe
ADC Therapeutics SA Europe
AlloCyte Pharmaceuticals AG Europe

Recent Private Companies Transactions

Type
Date
Target
No transactions available in the past 12 months.
 

The information and data displayed in this profile are created and managed by S&P Global Market Intelligence, a division of S&P Global. Bloomberg.com does not create or control the content. For inquiries, please contact S&P Global Market Intelligence directly by clicking here.

Stock Quotes

Market data is delayed at least 15 minutes.

Company Lookup

Most Searched Private Companies

Company Name Geographic Region
Lawyers Committee for Civil Rights Under Law United States
NYC2012, Inc. United States
Bertelsmann AG Europe
The Advertising Council, Inc. United States
Rush University United States

Sponsored Financial Commentaries

Sponsored Links

Request Profile Update

Only a company representative may request an update for the company profile. Documentation will be required.

To contact Octapharma AG, please visit www.octapharma.com. Company data is provided by S&P Global Market Intelligence. Please use this form to report any data issues.

Please enter your information in the following field(s):
Update Needed*

All data changes require verification from public sources. Please include the correct value or values and a source where we can verify.

Your requested update has been submitted

Our data partners will research the update request and update the information on this page if necessary. Research and follow-up could take several weeks. If you have questions, you can contact them at bwwebmaster@businessweek.com.