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November 25, 2015 7:21 AM ET


Company Overview of X-Rx, Inc.

Company Overview

X-Rx, Inc. develops drugs. The company was incorporated in 2012 and is based in Waltham, Massachusetts.

100 Beaver Street

Suite 101

Waltham, MA 02453

United States

Founded in 2012



Key Executives for X-Rx, Inc.

Chief Executive Officer
Age: 59
Executive Director
Compensation as of Fiscal Year 2015.

X-Rx, Inc. Key Developments

X-Rx Announces Autotaxin Inhibitor Collaboration with Gilead Sciences

X-Rx Inc. announced that it has entered into an exclusive agreement with Gilead Sciences, Inc. to develop X-Rx’s proprietary small molecule autotaxin (ATX) inhibitors. ATX plays a key role in maintaining tissue homeostasis and is upregulated in many diseases, including idiopathic pulmonary fibrosis (IPF). Inhibition of ATX leads to a reduction in lysophosphatidic acid production, which blocks signaling cascades that ultimately drive the development of fibrosis. Under the terms of the agreement, X-Rx will receive an upfront payment and research funding to advance the lead molecule through early clinical development and to support the company in further developing its other pipeline assets. X-Rx also may receive subsequent clinical milestone payments. X-Rx has granted Gilead the exclusive option to purchase the program.

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