Company Overview of MediciNova Inc.
MediciNova, Inc., a biopharmaceutical company, focuses on acquiring and developing novel and small molecule therapeutics for the treatment of serious diseases with unmet medical needs for the United States market. Its product candidates include MN-166 (Ibudilast), an anti-inflammatory and neuroprotective agent, which has completed Phase II clinical trials for the treatment of neurological disorders; MN-221 (Bedoradrine), a ß2-adrenergic receptor agonist that has completed Phase IIb clinical trails for the treatment of acute exacerbations of asthma; MN-001 (Tipelukast), an orally bioavailable small molecule compound, which has completed a pre-clinical study for the treatment of nonalcoholic s...
4275 Executive Square
La Jolla, CA 92037
Founded in 2000
Key Executives for MediciNova Inc.
Co-Founder, Chief Executive Officer, President and Executive Director
Total Annual Compensation: $504.8K
Head of Japanese Office and Vice President
Total Annual Compensation: $293.6K
Chief Medical Officer
Total Annual Compensation: $293.6K
Compensation as of Fiscal Year 2014.
MediciNova Inc. Key Developments
FDA Grants Fast Track Designation for Medicinova's MN-001 (Tipelukast) for the Treatment of Idiopathic Pulmonary Fibrosis
Sep 10 15
MediciNova Inc. announced that it has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for MN-001 (tipelukast) for the treatment of patients with idiopathic pulmonary fibrosis (IPF). In addition to the granting of Fast Track Designation to MN-001 for treatment of IPF, the FDA granted Orphan Drug Designation to MN-001 for treatment of IPF in October 2014, as previously announced.
MediciNova Inc. Presents at Ladenburg Thalmann 2015 Healthcare Conference, Sep-29-2015 03:30 PM
Sep 4 15
MediciNova Inc. Presents at Ladenburg Thalmann 2015 Healthcare Conference, Sep-29-2015 03:30 PM. Venue: Sofitel Hotel, New York, New York, United States. Speakers: Geoffrey G. O'Brien, Vice President, Yuichi Iwaki, Co-Founder, Chief Executive Officer, President and Executive Director.
MediciNova Announces First Advanced ALS Patient Using Non-Invasive Ventilation Support Enrolled in Phase 2 Clinical Trial of MN-166 (ibudilast)
Sep 3 15
MediciNova Inc. announced that the first advanced ALS patient, using non-invasive ventilation (NIV), has enrolled in the Phase 2 clinical trial evaluating MN-166 (ibudilast) in both early and advanced stage ALS. MediciNova amended the protocol to expand its recruitment to include advanced ALS patients in the trial, and this amendment was approved by FDA (U.S. Food and Drug Administration). The amended protocol now plans enrollment of 60 advanced ALS patients with NIV support in the study in addition to 60 patients without NIV support. Dr. Benjamin Rix Brooks, Director, Carolinas HealthCare System's Neuromuscular/ALS-MDA Center, is the Principal Investigator of the study. This is a single-center, randomized, double-blind, placebo-controlled, 6-month study designed to evaluate the safety, tolerability and clinical endpoint responsiveness of MN-166 (60 mg/day) when administered as an adjunct to riluzole (100 mg/day) in subjects with ALS. The protocol amendment plans for an additional 60 advanced ALS patients, who are on NIV support, to be enrolled in the study. This study consists of two treatment arms, MN-166 and matching placebo, and randomization will occur in a 2:1 ratio (MN-166: placebo). To be eligible, subjects must have a diagnosis of sporadic or familial ALS with onset of less than 10 years from first clinical weakness prior to screening, may be on NIV support, and must be on a stable dose of riluzole for at least 1 month prior to study drug treatment. A total of approximately 120 male and female subjects from 18 to 80 years old, inclusive, will be enrolled (80 subjects in the MN-166 group; 40 subjects in the placebo group). Upon completion of the Double-blind Phase, subjects randomized to the placebo arm will continue for an additional 6 months and will receive open-label MN-166. If there are no safety or tolerability concerns in the MN-166-treated group, a decision will be made to extend participation to the MN-166-treated group into the Open-Label Extension (OLE) Phase. Otherwise, only the placebo-treated patients will participate in the OLE Phase. The primary objective is to evaluate the safety and tolerability of MN-166 60 mg/day versus placebo when administered for 6 months with riluzole. The secondary objective is to evaluate the clinical endpoint responsiveness of MN-166 60 mg/day versus placebo when administered with riluzole as measured by the following assessments.
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