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August 29, 2015 4:15 PM ET


Company Overview of OncoCyte Corporation

Company Overview

OncoCyte Corporation develops genetically modified stem cells for finding malignant tumors while carrying genes that cause the destruction of the cancer cells. It offers PanC-Dx bladder cancer markers to the performance of cystoscopy. The company was founded in 2009 and is based in Alameda, California. OncoCyte Corporation operates as a subsidiary of BioTime, Inc.

1301 Harbor Bay Parkway

Alameda, CA 94502

United States

Founded in 2009





Key Executives for OncoCyte Corporation

Chief Executive Officer and Director
Chief Executive Officer of Biotime,Inc. and President of Biotime,Inc.
Age: 62
Chief Medical Officer
Compensation as of Fiscal Year 2015.

OncoCyte Corporation Key Developments

OncoCyte Corporation Announces Appointment of Andy Arno as Director

OncoCyte Corporation announced that Andy Arno has been appointed to the Company's Board of Directors. Andy Arno, 56, brings to the company a wealth of knowledge from his 30 years of capital markets experience working with emerging growth companies. He is currently Vice Chairman of The Special Equities Group at Chardan Capital Markets, LLC. He was previously Managing Director of Emerging Growth Equities, an investment bank, and Vice President of Sabr Inc., as well as President of LOMUSA Limited. From 2009 to 2012, Andy served as Vice Chairman and Chief Marketing Officer of Unterberg Capital, LLC. He also served as Vice Chairman and Head of Equity Capital Markets of Merriman Capital LLC and served on the board of its parent company, Merriman Holdings Inc. Mr. Arno currently serves on the boards of Asterias Biotherapeutics and Smith Micro Software Inc.

OncoCyte Corporation Announces Management Changes

OncoCyte Corporation announced that William Annett has been appointed Chief Executive Officer. Mr. Annett succeeds Joseph Wagner, PhD, who spearheaded the early stages of clinical development of OncoCyte’s product lines. With the departure of Dr. Wagner from the company and the board of the company, Mr. Annett will immediately take responsibility for leading the company through the later stages of clinical trials of OncoCyte’s proprietary, non-invasive diagnostic tests for cancer. Mr. Annett also assumes immediate responsibility for the development and execution of the commercial strategy for OncoCyte’s class of diagnostic tests. Having previously served as Chief Executive Officer of several companies, Mr. Annett brings to OncoCyte extensive experience within the biotechnology and diagnostics industry. In addition, Mr. Annett has held significant management positions at Genentech and Accenture and has worked on the clinical development and commercialization of a wide range of drugs and diagnostics. Mr. Annett’s diagnostics industry experience includes his service as CEO at BioFX Laboratories Inc. Most recently, Mr. Annett was a Managing Director at Accenture where he founded, built, and headed Accenture’s West Coast Life Sciences practice with sales, marketing, and delivery responsibilities for the entire territory.

BioTime, Inc. and OncoCyte Corporation Announce Positive Interim Results from Lung Cancer Study

BioTime, Inc. and OncoCyte Corporation have announced positive interim clinical results demonstrating the high level of observed sensitivity and specificity in the assayed samples of a simple blood-based test designed for the early detection of lung cancer. The large, prospective clinical study was conducted by The Wistar Institute. The test was developed in the laboratory of Louise Showe, PhD, professor in the Molecular and Cellular Oncogenesis program of The Wistar Institute's NCI-designated cancer center. As part of the study, clinical investigators used a simple collection system that is approved by the FDA to prepare over 600 peripheral blood samples from patients determined to be at high risk for developing lung cancer based on age and smoking history. These patients were undergoing either low-dose computed tomography (CT) scanning for lung cancer or were recently diagnosed with lung cancer. Wistar scientists then assessed the expression of messenger RNA and micro RNA in the initial training set of 242 samples and developed a classifier of 145 markers (125 mRNAs plus 20 micro RNAs) that most accurately distinguished patients with malignant nodules from those with benign or no findings. The classifier was then assessed in an independent test set of 103 samples. Performance of the classifier was evaluated using several criteria, including Receiver Operating Characteristic (ROC) area under the curve (AUC) analysis, and yielded an AUC of 0.88 (sensitivity of 76% with a specificity of 88%) in the test set. Analysis of the full patient sample set is near completion. In October 2013, OncoCyte entered into a Sponsored Research Agreement with The Wistar Institute to identify, develop and test potential lung cancer biomarkers collaboratively with Dr. Showe's laboratory. OncoCyte has exercised options to obtain exclusive licenses to any inventions, discoveries or technology developed in the course of the collaborative research, including the technology presented and expects to negotiate definitive license agreements with Wistar.

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