October 21, 2016 12:38 PM ET


Company Overview of Avelas BioSciences, Inc.

Company Overview

Avelas BioSciences, Inc. is a clinical stage biotechnology company that focuses on developing technologies that advance care for cancer surgery and therapeutic intervention. It develops AVB-620, an intravenously administered in vivo fluorescent protease-activatable peptide that detects, marks, and diagnoses cancer. The company was incorporated in 2008 and is based in La Jolla, California.

11099 North Torrey Pines Road

Suite 290

La Jolla, CA 92037

United States

Founded in 2008





Key Executives for Avelas BioSciences, Inc.

Chief Executive Officer, President and Director
Age: 40
Co-Founder and Research Collaborator
Age: 64
Vice President of Clinical Affairs
Clinical Advisor
Age: 47
Compensation as of Fiscal Year 2016.

Avelas BioSciences, Inc. Key Developments

Avelas BioSciences, Inc. Presents at 2016 BIO Investor Forum, Oct-19-2016 02:00 PM

Avelas BioSciences, Inc. Presents at 2016 BIO Investor Forum, Oct-19-2016 02:00 PM. Venue: Westin St. Francis Hotel, 335 Powell Street, San Francisco, CA 94102, United States.

Avelas BioSciences, Inc. Completes Patient Enrollment for AVB-620 Phase 1b Clinical Trial

Avelas Biosciences, Inc. announced the completion of patient enrollment in its Phase 1b clinical trial for AVB-620, a surgical marker, in women with primary, non-recurrent breast cancer undergoing surgery. Avelas will announce data from the trial at a future medical meeting. AVB-620 Phase 1b Clinical Program: Fifteen patients were enrolled in the initial dose-escalation portion of the Phase 1b trial, the purpose of which was to evaluate safety and pharmacokinetics and to determine the dose for additional imaging analysis in the second stage of the study. Interim analysis showed no toxicity issues and identified a preferred dose to take forward into the expansion phase of the trial. A total of 12 additional patients have been enrolled in the dose-expansion stage of the trial, where the focus remains on safety, pharmacokinetics, and the timing of imaging after AVB-620 administration. The company expects to announce data from its completed Phase 1b trial later 2016. AVB-620 is an intravenously administered in vivo fluorescent protease-activatable peptide that detects, labels, and visualizes cancer. The initial potential use for AVB-620 is the intraoperative identification of primary tumor extent and metastatic lymph nodes in breast cancer patients. AVB-620 displayed outstanding preclinical data with sensitivity of greater than 95% in preclinical breast cancer models and ex vivo analysis of human breast cancer tissue.

Avelas BioSciences, Inc. Announces Executive Changes

Avelas Biosciences, Inc. announced that Andrei Petrov has joined the company's board of directors. Dr. Petrov is the chief executive officer and managing partner at Inbio Ventures. At the same time, Kevin Kinsella and Nikolay Savchuk will be stepping down as directors of the company.

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