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July 04, 2015 8:49 PM ET

Healthcare Equipment and Supplies

Company Overview of BioCision, LLC

Company Overview

BioCision, LLC develops portable benchtop tools for temperature sensitive biomedical samples for basic and clinical research and diagnostics. It offers cell freezing containers microfuges, storage, portable ice-free cooling/freezing, cool and thermaltrays, ergotubes, accessories, and clinic products. The company’s products are used by researchers in bio-pharma, academic research, clinical research and diagnostics, hospital, government, industry, and medical devices customers. It offers products through distributors in the United States, Canada, Europe, Asia, the Middle East, Australia, and New Zealand; and online. The company was founded in 2007 and is based in Larkspur, California.

12 East Sir Francis Drake Boulevard

Suite B

Larkspur, CA 94939

United States

Founded in 2007





Key Executives for BioCision, LLC

Chief Executive Officer, President and Director
Chief Financial Officer
Vice President of Operations
President of Dark Horse Consulting
Chief Commercialization Officer
Compensation as of Fiscal Year 2015.

BioCision, LLC Key Developments

BioCision, LLC to Develop Customized ThawSTAR Automated Cell Thawing System for Celgene Cellular Therapeutics

BioCision, LLC announced that it will collaborate with Celgene Cellular Therapeutics (CCT) to accelerate the development of a cell thawing solution based on BioCision's proprietary ThawSTAR™ technology for the 6 mL injectable vial that CCT has chosen to store PDA-002, a cryopreserved, allogeneic cell therapy currently in clinical development to treat diabetic foot ulcers in patients with peripheral arterial disease. Conventional thawing methods, including swirling vials in warm water baths or rolling vials between hands can result in variable cell viabilities and can increase contamination concerns. BioCision’s ThawSTAR system utilizes a patent pending adaptive sensing technology that incorporates algorithms to deliver a consistent and reproducible thaw profile and endpoint to each vial, thus providing a standardized thawing process, eliminating variability that could have a detrimental effect on the safety and efficacy of the cell therapy, and providing a significant reduction in cell handling risk in a clinical setting. The new ThawSTAR automated cell thawing system that will be developed as a result of this collaboration is an expansion of BioCision’s technology platform and will be made available commercially. BioCision is also developing other vial formats to address the needs of the larger cell therapy market.

BioCision, LLC and Brooks Automation, Inc. Announce Joint Development Partnership to Unveil New Cryogenic Sample Handling and Transport Product

BioCision, LLC and Brooks Automation announced their collaborative research and development agreement to improve the handling and transport of valuable biospecimens stored in liquid nitrogen is progressing to the commercialization stage. The co-development project between BioCision and Brooks began in mid-2014 with the goal of providing tools that enable more rigorous collection, handling, and transporting of temperature-sensitive specimens and therapeutics. Current methods, including placing samples stored at liquid nitrogen temperature (-196 C) onto dry ice, which is considerably higher in temperature at -78 C, or utilizing makeshift transporters such as pans with loose liquid nitrogen, leave samples vulnerable to drastic temperature shifts and potentially place operators at risk with insufficient safeguards in place for handling loose liquid nitrogen. The result of this collaboration will be revealed at the upcoming 2015 meeting of the International Society for Biological and Environmental Repositories (ISBER).

Biocision Announces Availability of ThawSTAR Automated Sample Thawing System

BioCision, LLC announced the availability of ThawSTAR(TM) automated sample thawing system, a breakthrough technology that addresses the 'last mile' in the cryopreservation process. Utilizing the patent-pending STAR(TM) sensing technology, ThawSTAR system tailors the thaw cycle to the specific characteristics of each frozen sample. Consistent with BioCision's objective to standardize important workflows, the ThawSTAR technology platform represents another industry first and sets a new standard for how cells and cell-based therapies are thawed. The ThawSTAR technology integrates multiple detection algorithms to ensure uniform thermal profiles and reproducible recovery of the frozen contents, eliminating the subjectivity found in conventional thaw methods that rely on human interpretation, such as swirling frozen vials in water baths, rolling vials between hands and other crude methods. Each of these outdated methods carries a high level of risk for temperature variation and sample contamination, important considerations in the preparation of cells, including cell therapy drugs. Like other BioCision products, ThawSTAR sample thawing system is an intuitive, error-free method for achieving reproducible thawing and recovery results. Users will simply insert a frozen vial and retrieve it when the vial is raised at the end of the thaw cycle. The automatic release of the vial coupled with built-in audio and visual alarms allow users to quickly retrieve thawed vials for downstream processing to minimize risk of toxicity from cryopreservatives, such as DMSO. ThawSTAR thawing system was engineered to deliver results similar to those achieved when thawing in a 37C water bath, but with reproducibility and standardization built in. Its small footprint enables easy incorporation into a laboratory or clinical setting. BioCision will feature ThawSTAR sample thawing system at the upcoming American Society for Cell Biology meeting in Philadelphia, PA December 6-10, booth number 725.

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