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November 30, 2015 6:39 AM ET


Company Overview of Hepregen Corporation

Company Overview

Hepregen Corporation develops bio-engineered solutions for drug discovery and development applications in the pharmaceutical industry. The company develops and commercializes HepatoPac, a bio-engineered micro-liver platform for use in a range of applications, including metabolite identification, toxicity screening, clearance, drug-drug interactions, transporter involvement, in silico models, toxicogenomics, and disease modeling applications in humans; and HepatoMune, a micro-liver assay kit to predict toxicologic outcomes caused by the interaction of drugs and/or biologics with an inflamed liver. Its solutions are also used in cosmetic and environmental testing industries. The company was fo...

200 Boston Avenue

Suite 1500

Medford, MA 02155

United States

Founded in 2007





Key Executives for Hepregen Corporation

Chief Executive Officer and Director
Age: 68
Co-Founder, President and Director
Co-Founder and Director of Research
Chief Financial Officer and Vice President of Finance and Administration
Age: 61
Vice President of Operations
Compensation as of Fiscal Year 2015.

Hepregen Corporation Key Developments

BioTime, Inc. Announces Joint Venture with Hepregen Corporation

BioTime, Inc. and Hepregen Corporation have formed a joint venture company Ascendance Biotechnology, Inc. focused on the in vitro cell biology. As part of the transaction, Ascendance combines Hepregen's application-directed, cellular micro-patterning drug and chemical screening technologies with BioTime's ESI BIO research products and proprietary stem cell technologies. Ascendance will offer a portfolio of current and new stem-cell-derived assays and other products and services to pharmaceutical and chemical companies. In exchange for its contribution of certain assets relating to its research products and related patents and technology, BioTime will acquire a majority equity position in Ascendance. Ascendance will continue to market Hepregen's well-known HepatoPac(R) and HepatoMune(R) micro-patterned liver products, and plans to develop new and unique cell-based and micro-patterned products using BioTime's stem cell technologies and broad intellectual property and product portfolio, including BioTime's PureStem(R) embryonic progenitors and ESI embryonic stem cells. Ascendance also expects to develop additional stem-cell-derived products that will be useful for toxicity testing in the cosmetic, environmental, and food industries.

SOLVO Biotechnology and Hepregen Corp. Sign Co-Marketing Pact

SOLVO Biotechnology and Hepregen Corp. reported the Study of Xenobiotics, a co-marketing agreement between the companies. This agreement provides for the European marketing of Hepregen's human, monkey, rat and dog application-directed HepatoPac and HepatoMune kits, which are used for liver metabolite analysis, transport studies and predictive and mechanistic toxicology studies. These kits contain human or animal hepatocytes (liver cells) in Hepregen's proprietary micro-patterned, co-culture microtiter tissue culture plates. This agreement provides SOLVO with the opportunity to make services available to its customers using these Hepregen products as well as HepatoPac B-CLEAR products co-developed by Hepregen and Qualyst Transporter Solutions.

Hepregen Corporation Launches First Dog HepatoPac Assay Kit to Evaluate Metabolism in the Laboratory

Hepregen Corporation announced the commercial launch of the company's first dog HepatoPac kit designed specifically for metabolite identification and profiling applications. Each kit contains one or more standard 24-well tissue culture plates featuring uniquely configured micro-patterned dog liver cells co-cultured with specially selected stromal cells that support the high level of performance observed in Hepregen's micro-patterned co-culture platform. The dog liver cells (hepatocytes) on these plates mirror the behavior of liver cells in live animals, enabling scientists to generate data that can be useful for evaluation of the metabolism of chemical agents, including drug candidates, improving the design of preclinical experiments. The remarkable flexibility of Hepregen's micro-patterned HepatoPacĀ® platform allowed Hepregen scientists to develop a dog product that provides investigators with uniquely stable canine hepatocytes. The tissue culture maintains functionality and morphology for weeks, enabling experiments not previously possible.

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