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February 12, 2016 6:11 AM ET


Company Overview of NeoStem Oncology, LLC

Company Overview

NeoStem Oncology, LLC discovers, produces, and supplies human cell populations for research, diagnostic, clinical, and therapeutic applications. The company offers stem cell media, such as serum-free media for propagation of human embryonic stem cell (hESC); serum-free media for propagation of human myoblasts; serum-free media formulation to propagate hESC and bias their differentiation to ectodermal lineages; and products for laboratory research purposes. The company also provides human motor neuron progenitors, human cardiac progentior cells, and human neuronal progentior cells for screening and predictive toxicology applications, which are derived from human embryonic stem cells. In addit...

5251 California Avenue

Suite 150

Irvine, CA 92617

United States

Founded in 2005



Key Executives for NeoStem Oncology, LLC

Chairman of The Scientific Advisory Board, Chief Executive Officer, and President
Chief Financial Officer
Age: 45
Chief Medical Officer
Age: 68
Vice President of Research and Development
Compensation as of Fiscal Year 2015.

NeoStem Oncology, LLC Key Developments

Neostem, Inc., California Stem Cell, Inc. - M&A Call

To discuss the definitive agreement to acquire California Stem Cell, Inc

U.S. Food and Drug Administration Approves California Stem Cell, Inc.'s Phase II Cancer Stem Cell Clinical Trial for Ovarian Cancer

California Stem Cell, Inc. announced that the U.S. Food and Drug Administration has approved the company's application to begin a Phase II clinical trial exploring the potential of a patient specific cancer immunotherapy in women with Stage III or IV ovarian, fallopian tube or primary peritoneal cancer. The randomized, double blind study is the company's second cancer therapy approved for clinical trials by the FDA, bolstering its platform approach to treating late stage solid-tumor cancers. The company's patient specific approach to treating metastatic melanoma, recently approved to begin a Phase III trial, provided sufficient safety data to proceed directly to a Phase II study in ovarian cancer. The study design randomizes an estimated 99 adult female patients to two treatment arms. The treatment group will receive Ovapuldencel-T, which is a combination of autologous dendritic cells loaded with irradiated autologous tumor cells in GM-CSF. Ovapuldencel-T is created by first isolating cancer stem cells from the patient's resected tumor sample, then enriching, inactivating and combining these cells with dendritic cells or antigen presenting immune cells which are harvested from the patient's blood. The control group will receive the ‘MC’ treatment, harvested from the patient's blood combined with GM-CSF, granulocyte macrophage colony stimulating factor, a white blood cell growth factor. The trial design calls for both groups to receive subcutaneous injections of their respective treatment weekly for three consecutive weeks, then monthly for the following five months. The trial is expected to last approximately sixty months, including enrollment, treatment, and long term patient follow-up.

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