Company Overview of University of California-San Francisco
University of California-San Francisco is an education institution offering programs such as biological, biomedical, pharmaceutical, nursing, social and behavioral sciences, dentistry, medicine, and nursing and pharmacy. The schools of the university include Continuing Medical Education, School of Dentistry, School of Medicine, School of Nursing, and School of Pharmacy. University of California- San Francisco was established in 1897 and is based in San Francisco, California. The university has endowment assets worth $873 million.
San Francisco, CA 94143
Founded in 2007
Key Executives for University of California-San Francisco
Professor of Tumor Biology and Cancer Research, Department of Microbiology and Immunology
Executive Director of News
Executive Director of Global Health Sciences
Compensation as of Fiscal Year 2015.
University of California-San Francisco Key Developments
University of California-San Francisco Presents at Milken Institute, Global Conference 2015, Apr-27-2015 10:45 AM
Apr 17 15
University of California-San Francisco Presents at Milken Institute, Global Conference 2015, Apr-27-2015 10:45 AM. Venue: 2025 Ave Of The Stars, Los Angeles, CA 90067, California, United States. Speakers: Atul Butte, Director, Institute of Computational Health Sciences.
BioMotiv, University of California San Francisco and University of Washington Announces Formation of Optikira
Feb 2 15
BioMotiv, the University of California San Francisco and University of Washington are announcing the formation of OptiKira, a platform company that will develop small molecule therapeutics that prevent cell death in pathologies caused by misfolded or unfolded proteins. OptiKira is based on intellectual property exclusively licensed from UCSF and University of Washington. The project was initiated at UCSF and the University of Washington by scientific founders Scott Oakes, MD, Associate Professor of Pathology at UCSF, Feroz Papa, MD, PhD, Associate Professor of Medicine at UCSF, Bradley Backes, PhD, Associate Professor of Medicine at UCSF, and Dustin Maly, PhD, Associate Professor in Chemistry at University of Washington. Dr. Oakes and Dr. Papa are members of the first class of Harrington Scholar-Innovators. Extensive research by the Founders has helped define the biological pathway leading to progressive cell death which characterizes diseases such as retinitis pigmentosa, diabetes, and amyotrophic lateral sclerosis (ALS). They have found that the Unfolded Protein Response (UPR), a mechanism by which the cell deals with functionally abnormal proteins, has an important housekeeping role in cell metabolism. However when overloaded, the 'terminal UPR' results in the accumulation of excessive unfolded proteins and cellular death. The team has synthesized inhibitors of IRE1a to prevent the activation of the terminal UPR, while not disrupting the housekeeping role of the enzyme. They have demonstrated that inhibitors of IRE1a, which they have named kinase-inhibiting RNase attenuators (KIRAs), protect cells from degeneration in preclinical models of retinitis pigmentosa and diabetes.
University of California San Diego and University of California San Francisco Launch New Cancer Cell Mapping Initiative
Jan 29 15
Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project - dubbed the Cancer Cell Map Initiative or CCMI - to determine how all of the components of a cancer cell interact. In recent years, progress in genome sequencing has made it possible to decipher hundreds of mutations found in a patient's tumor. But in only a few cases do scientists understand how these mutations give rise to cancer or indicate what treatments to pursue. More puzzling still, the mutations found in each patient are almost always different - even though they can lead to the same type of cancer. It has long been thought that, while these mutations are unique to individuals, they hijack the same hallmark cancer pathways or genetic circuits. To interpret genomic data, researchers say the complete wiring diagram of the cell is needed, one that details all of the connections between normal and mutated genes and proteins. The CCMI will provide key infrastructure for the recently announced alliance between UC San Diego Health Sciences and San Diego-based Human Longevity Inc., which plans to generate thousands of tumor genomes from UC San Diego cancer patients. It will also leverage resources and information from the National Cancer Institute (NCI), including large databases of cancer genomes and pathways that are being developed in collaboration with the San Diego Supercomputer Center and UC Santa Cruz.
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