January 24, 2017 8:18 AM ET


Company Overview of Genocea Biosciences, Inc.

Company Overview

Genocea Biosciences, Inc., a biopharmaceutical company, discovers and develops novel vaccines and immunotherapies to treat infectious diseases. The company uses its proprietary discovery platform AnTigen Lead Acquisition System to design vaccines and immunotherapies that act through T cell immune responses. Its lead product candidate is GEN-003, a therapeutic vaccine or immunotherapy that is in Phase 2 trial for the treatment of genital herpes infections. It is also developing GEN-001, a product candidate that is in pre-clinical stage for treating chlamydia prophylaxis; GEN-002, which is in pre-clinical stage for the treatment of genital herpes prophylaxis; and GEN-005 that is in research st...

100 Acorn Park Drive

5th Floor

Cambridge, MA 02140

United States

Founded in 2006

87 Employees





Key Executives for Genocea Biosciences, Inc.

Chief Executive Officer, President and Director
Age: 47
Total Annual Compensation: $427.4K
Chief Financial Officer and Secretary
Age: 41
Total Annual Compensation: $328.0K
Chief Medical Officer
Age: 64
Total Annual Compensation: $378.7K
Compensation as of Fiscal Year 2015.

Genocea Biosciences, Inc. Key Developments

Genocea Biosciences, Inc. - Special Call

To discuss Positive GEN-003 Phase 2b 6-Month

Genocea Biosciences, Inc. - Special Call

To discuss positive GEN-003 phase 2b six month results

Genocea Biosciences, Inc. Announces Positive Clinical Results from Planned Interim Analysis of Ongoing Placebo-Controlled Phase 2b Trial Evaluating Gen-003 for the Treatment of Genital Herpes Infections

Genocea Biosciences, Inc. announced positive clinical results from a planned interim analysis of its ongoing placebo-controlled Phase 2b trial evaluating GEN-003 for the treatment of genital herpes infections. Even in a trial this small, at six months after dosing, GEN-003 demonstrated statistically significant improvements versus placebo across multiple clinical endpoints. The 60 µg per antigen /50 µg of adjuvant dose of GEN-003 significantly reduced the rate of genital lesions during the six months following dosing compared to placebo (4.5% of days vs. 7.9%, respectively; 41% reduction vs. placebo, p<0.05). The genital lesion rate is an important overall measure of disease that captures both the frequency and duration of recurrences, both of which are important to both patients and their caregivers. In the trial, GEN-003 also consistently demonstrated significant benefits versus placebo across several other clinical endpoints across the dose groups. In aggregate, the data from the GEN-003 Phase 2 clinical trials continue to support the selection of the 60 µg per antigen /50 µg of adjuvant dose for the planned Phase 3 program. GEN-003 also continues to demonstrate a safety profile appropriate for its therapeutic setting in the judgment of the trial’s independent Drug Monitoring Committee.

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