July 27, 2017 5:22 AM ET


Company Overview of Lycera Corp.

Company Overview

Lycera Corp., a biopharmaceutical company, develops oral immune modulators for the treatment of patients with autoimmune diseases and cancer. Its product pipeline includes LYC-30937, an ATPase modulator for the treatment of inflammatory bowel disease; oral RORgamma agonists for diverse applications in immune-oncology; and Rho kinase inhibitors, histone deacetylase 6 inhibitors, RORgt antagonists, and collaboration targets. Lycera Corp. was founded in 2006 and is headquartered in Ann Arbor, Michigan.

2800 Plymouth Road


Building 26

Ann Arbor, MI 48109

United States

Founded in 2006



Key Executives for Lycera Corp.

Chief Executive Officer, President and Director
Age: 59
Chief Financial Officer
Senior Vice President of Biology
Chief Medical Officer
Compensation as of Fiscal Year 2017.

Lycera Corp. Key Developments

Lycera Corp. Presents at BIO International Conference 2017, Jun-19-2017 02:30 PM

Lycera Corp. Presents at BIO International Conference 2017, Jun-19-2017 02:30 PM. Venue: San Diego Convention Center, San Diego, CA 2865, United States. Speakers: Paul J. Sekhri, Chief Executive Officer, President and Director.

Lycera Corp. Announces Board Changes

Lycera Corp. announced that Pablo J. Cagnoni, M.D., has been elected to the company's Board of Directors, effective immediately. The company also announced that Timothy M. Mayleben will step down from his position on Lycera's Board. Dr. Cagnoni is President and Chief Executive Officer of Tizona Therapeutics.

Lycera Corp. Announces Initiation of Phase 1/2a Study Argon of Immuno-Oncology Candidate LYC-55716 in Patients with Advanced Solid Tumors

Lycera Corp. announced the initiation of a Phase 1/2a clinical trial of the company's novel immuno-oncology therapeutic candidate LYC-55716, in patients with advanced, relapsed, or refractory solid tumors. The ARGON trial (Trial of RORgamma Agonist LYC-55716 in Advanced Cancer) is a Phase 1/2a study of LYC-55716 in patients with advanced, relapsed or refractory solid tumors. The initial Phase 1 portion of the study is designed to find the biologically active or maximum tolerated dose of LYC-55716. The study will utilize a 3+3 study design, in which LYC-55716 will be administered orally in subjects with relapsed or refractory solid tumors. The primary endpoints are safety and tolerability, and the study is designed to determine the maximum tolerated dose (MTD) and the recommended Phase 2 dose. Upon dose determination, LYC-55716 will enter Phase 2a, which is expected to enroll approximately 40 patients. The primary efficacy endpoint of the Phase 2a portion of the study will be objective response rate according to response evaluation criteria in solid tumors.

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