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August 01, 2015 10:53 PM ET

Pharmaceuticals

Company Overview of Prolong Pharmaceuticals, LLC

Company Overview

Prolong Pharmaceuticals, LLC, a biopharmaceutical company, develops products for the treatment of anemia resulting from oxygen deficiency and hemolysis. It offers SANGUINATE, an investigational bio-pharmaceutical product that facilitates the transfer of oxygen to oxygen-deprived cells and tissues and down-regulates the inflammatory response in blood samples of sickle cell disease (SCD) patients. The company’s products also include ANF-Rho to create a novel molecule with a unique mechanism of action; EPEG, a long-acting 3rd generation PEGylated EPO biologic for the treatment of anemia; and PP-403, a novel cytokine with applications in cancer; and hematology products. Prolong Pharmaceuticals, ...

1 Cragwood Road

Suite 203

South Plainfield, NJ 07080

United States

Founded in 2002

Phone:

908-444-4660

Fax:

908-444-4661

Key Executives for Prolong Pharmaceuticals, LLC

Founder, Chief Executive Officer, Chief Scientific Officer and Director
President
Age: 54
Vice President of Information Services
Director of Development
Vice President of Quality
Compensation as of Fiscal Year 2015.

Prolong Pharmaceuticals, LLC Key Developments

Prolong Pharmaceuticals, Inc. Presents at The 2nd Annual Sachs Cancer Bio Partnering & Investment Forum, Mar-19-2014 04:15 PM

Prolong Pharmaceuticals, Inc. Presents at The 2nd Annual Sachs Cancer Bio Partnering & Investment Forum, Mar-19-2014 04:15 PM. Venue: New York Academy of Sciences, New York, United States.

Prolong Pharmaceuticals LLC Appoints Ronald G Jubin as Managing Director, Research and Development

Prolong Pharmaceuticals LLC named Ronald G Jubin, PhD as its managing director, Research and Development. The new managing director, Research and Development will be responsible for pre-clinical discovery, methods development and the advancement of the company's pipeline candidates.

Prolong Announces Encouraging Results from Phase I Hemolytic Disorder Study

Prolong Pharmaceuticals LLC, a biopharmaceutical company, has announced results from its Phase I study of the company's lead product, SANGUINATE. SANGUINATE (PEGylated carboxyhemoglobin bovine) is an intravenous therapeutic that combines the beneficial functions of a carbon monoxide releasing molecule (CORM) with an oxygen transfer agent (OTA) as well as acting as a plasma expander/flow enhancer. Results from animal studies indicate that low dose release of carbon monoxide promotes anti-inflammatory and anti-vasoconstriction effects, while oxygen is actively delivered to regions of low oxygen concentration (ischemia). The Phase I study was a single center, single-blind, placebo-controlled, single dose study of the safety, tolerability and pharmacokinetics of SANGUINATE in healthy subjects. Three dose levels of SANGUINATE (80 mg/kg, 120 mg/kg, and 160 mg/kg) were administered by intravenous infusion to 3 groups. Each group included 8 subjects: 6 subjects who received active treatment (SANGUINATE) and 2 subjects who received placebo comparator (saline). Overall, SANGUINATE was found to be well tolerated. There were no serious adverse events in this study and there were no discontinuations due to adverse events.

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