October 20, 2017 12:57 PM ET

Pharmaceuticals

Company Overview of Semnur Pharmaceuticals, Inc.

Company Overview

Semnur Pharmaceuticals, Inc. develops and markets non-opioid drugs to treat back pain. The company was incorporated in 2013 and is based in Los Altos, California.

4970 El Camino Real

Suite 205

Los Altos, CA 94022

United States

Founded in 2013

Phone:

888-315-8706

Key Executives for Semnur Pharmaceuticals, Inc.

Chief Executive Officer and Director
Age: 57
Executive Director
Age: 72
Compensation as of Fiscal Year 2017.

Semnur Pharmaceuticals, Inc. Key Developments

Semnur Pharmaceuticals, Inc. Announces Successful Phase 1 / 2 Trial in Patients with Radicular Pain for its Lead Product, SP-102

Semnur Pharmaceuticals, Inc. announced successful Phase 1 /2 pharmacokinetic bridging trial of the lead product SP-102. The trial was conducted in the patients with radicular pain, achieved its primary pharmacokinetic endpoint, and also demonstrated that a single epidural injection of SP-102 can lead to a sustained analgesic effect lasting one month. SP-102 is the first non-opioid novel gel formulation in development for the treatment of lumbar radicular pain, containing no neurotoxic preservatives, surfactants, solvents or particulates. The SP-102 formulation is administered by epidural injection and extends the residency time at the site of injection based on preclinical and patient studies. The trial also showed that adverse events were comparable between the two treatments. There were no serious adverse events (SAE) and SP-102 injections were well tolerated. The single epidural injection of SP-102 showed a clear trend in a sustained analgesic effect, lasting over the entire observational period of one month, demonstrated by Mean 20% to 40% reductions of daily average back and leg pain in 12 subjects enrolled in the study.

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