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April 26, 2015 2:29 AM ET

Pharmaceuticals

Company Overview of Edison Pharmaceuticals, Inc.

Company Overview

Edison Pharmaceuticals, Inc. develops medicines for the treatment of inherited mitochondrial diseases. It offers EPI-743 and EPI-A0001 orally absorbed small molecules. Edison Pharmaceuticals, Inc. has a strategic alliance with Dainippon Sumitomo Pharma Co., Ltd. The company was founded in 2005 and is based in Mountain View, California with additional offices in the Netherlands. Edison Pharmaceuticals, Inc. operates as a subsidiary of Galileo Pharmaceuticals, Inc.

350 North Bernardo Avenue

Mountain View, CA 94043

United States

Founded in 2005

Phone:

408-960-2910

Fax:

408-413-5300

Key Executives for Edison Pharmaceuticals, Inc.

Chairman and Chief Executive Officer
Corporate Counsel and Secretary
Age: 55
Vice President of Intellectual Property
Vice President of Research & Development
Compensation as of Fiscal Year 2014.

Edison Pharmaceuticals, Inc. Key Developments

Edison Pharmaceuticals, Inc. Presents at 33rd Annual J.P. Morgan Healthcare Conference, Jan-13-2015 02:00 PM

Edison Pharmaceuticals, Inc. Presents at 33rd Annual J.P. Morgan Healthcare Conference, Jan-13-2015 02:00 PM. Venue: Westin St. Francis Hotel, San Francisco, California, United States. Speakers: Guy Miller, Chairman and Chief Executive Officer.

Edison Pharmaceuticals, Inc. Announces Phase 2 Positive Clinical Results for EPI-743 in Rett Syndrome

Edison Pharmaceuticals, Inc. announced results of a recently completed phase 2 placebo-controlled trial in pediatric patients. Rett syndrome patients treated with EPI-743 demonstrated a statistically significant increase in head circumference. Decreased brain growth and head circumference are hallmarks of the disease. Rett syndrome is a genetic neurodevelopmental disorder predominately affecting girls, and is usually diagnosed by 24 months of age. It is characterized by a constellation of neurological, behavioral, functional, and structural features. These include delayed development, characteristic hand wringing, seizures, impaired respiratory function, slowing of brain growth, and resultant diminished head size, as well as other neurological disorders. The double-blind, placebo-controlled clinical trial was conducted at the General University Hospital (Azienda Ospedaliera Universitaria Senese) of Siena. A total of 24 subjects, 2.5 to 8 years of age, were enrolled in the six-month trial. While the study did not meet the primary endpoint of improving the subjective Rett syndrome disease severity score, subjects treated with EPI-743 demonstrated an objective improvement in head growth. Specifically, head growth in the treatment group was 0.75 cm from baseline, compared to 0.29 cm in the placebo group (p=0.05). In a subgroup analysis of the children with the large head growth, improvements in oxygenation, hand function, and disease-relevant biomarkers were also recorded. These data will be submitted for publication in the near future.

Edison Pharmaceuticals, Inc. Presents at Baird's 2014 Healthcare Conference, Sep-04-2014 08:25 AM

Edison Pharmaceuticals, Inc. Presents at Baird's 2014 Healthcare Conference, Sep-04-2014 08:25 AM. Venue: The New York Palace, New York, New York, United States.

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