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April 17, 2015 11:45 PM ET

Healthcare Equipment and Supplies

Company Overview of CardioDx, Inc.

Company Overview

CardioDx, Inc. operates a molecular diagnostics company that develops and commercializes proprietary tests to help improve treatment decisions, enhance patient outcomes, and reduce the overall cost of care. The company’s initial focus is on diagnostics for cardiovascular diseases, specifically coronary artery disease (CAD), arrhythmia, and heart failure. Its solution includes Corus CAD test, which is a commercially available blood-based gene expression test that provides an assessment for non-diabetic patients with symptoms that are suggestive of obstructive CAD. The company markets its Corus CAD test to healthcare providers through its direct sales force in the United States. CardioDx, Inc....

600 Saginaw Drive

Redwood City, CA 94063

United States

Founded in 2003

146 Employees


650 475 2788


650 475 2799

Key Executives for CardioDx, Inc.

Founder, Chief Executive Officer, President and Director
Age: 54
Vice President of Operations
Chief Medical Officer
Age: 53
Head of Corporate Development and General Counsel
Compensation as of Fiscal Year 2014.

CardioDx, Inc. Key Developments

CardioDx, Inc. Announces the Results of Study Demonstrating the Benefits of the Corus Cad Gene Expression Test

CardioDx, Inc. announced the presentation of the study. The study evaluated the clinical utility of the Corus CAD blood-based gene expression test in the assessment of 518 African American patients presenting with symptoms suggestive of obstructive coronary artery disease (CAD) in a primary care setting. The results demonstrate the impact of Corus CAD score on clinician decision-making: Patients with low-Corus CAD scores (= 15) had a 95% decreased rate of referral for advanced cardiac testing compared to patients with elevated (> 15) Corus CAD scores (8/214 vs. 227/304). By ruling out obstructive CAD early in the work-up, the Corus CAD test was able to help clinicians avoid unnecessary referrals to cardiology or advanced cardiac testing when their patients' symptoms are due to non-cardiac causes. Corus CAD is the first and only commercially available blood-based test incorporating age, sex, and gene expression measurements that provides a current-state assessment of obstructive CAD in non-diabetic patients presenting with non-acute typical or atypical symptoms. The results of the gene expression measurements are combined with the patient's age and sex in an algorithm that delivers a score representing the likelihood of obstructive CAD. With a 96% negative predictive value, Corus CAD can help clinicians accurately rule out obstructive CAD as the source of their patients' symptoms, so that they may investigate other non-cardiac causes. Of the 518 patients enrolled in the study, 41% (n=214) had a low Corus CAD score, demonstrating that the test has high relevance to clinical practice for ruling out obstructive CAD in a significant number of patients in everyday practice. The authors concluded that Corus CAD improved care for those patients with a low score by avoiding unnecessary, and potentially invasive, advanced diagnostic testing.

CardioDx Announces New Leadership Appointments

CardioDx, Inc. announced that diagnostics industry veterans Melinda Griffith, J.D., and Doug Ross, M.D., Ph.D., have joined the executive team as Head of Corporate Development and General Counsel, and Chief Scientific Officer, respectively. In addition, the company has announced the appointment of James Tobin and Andrew Guggenhime to the Board of Directors. Andrew Guggenhime will be transitioning from his role as Chief Financial Officer of CardioDx to this new position. Prior to joining CardioDx, Ms. Griffith served in multiple executive management positions at Clarient, Inc. Most recently, Dr. Ross was an independent consultant serving as Acting Chief Scientific Officer of the Medical Science division of Life Technologies Corporation, helping guide research and development as well as strategic partnerships initiatives. With more than 40 years of healthcare industry experience, Mr. Tobin previously served as CEO and President of Boston Scientific Corporation. Mr. Guggenhime brings strong leadership, management, business, and financial expertise from the life sciences sector to the CardioDx Board of Directors. Mr. Guggenhime joined CardioDx as Chief Financial Officer in September 2011.

CardioDx, Inc. Auditor Raises 'Going Concern' Doubt

CardioDx, Inc. filed its S-1/A on Apr 28, 2014 for the period ending Dec 31, 2013. In this report its auditor, Ernst & Young LLP, gave an unqualified opinion expressing doubt that the company can continue as a going concern.

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