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November 29, 2015 9:19 AM ET

Healthcare Equipment and Supplies

Company Overview of CardioDx, Inc.

Company Overview

CardioDx, Inc., a molecular diagnostics company, develops tests for coronary artery disease (CAD), cardiac arrhythmia, and heart failure. It develops Corus CAD, a blood test that helps primary care clinicians and cardiologists to assess whether or not non-diabetic patient’s chest discomfort or other symptoms are due to obstructive CAD. The company serves customers in the United States. CardioDx, Inc. was incorporated in 2003 and is based in Redwood City, California.

600 Saginaw Drive

Redwood City, CA 94063

United States

Founded in 2003

146 Employees


650 475 2788


650 475 2799

Key Executives for CardioDx, Inc.

Founder, Chief Executive Officer, President and Director
Age: 55
Chief Medical Officer
Age: 54
Senior Vice President of Human Resources
Age: 54
Vice President of Development
Senior Vice President of Sales
Age: 56
Compensation as of Fiscal Year 2015.

CardioDx, Inc. Key Developments

CardioDx, Inc. and Quest Diagnostics Sign Agreement to Expand Patient Access to the Corus Cad Test

CardioDx, Inc. announced a national specimen-draw agreement with Quest Diagnostics that will expand patient and clinician access to the Corus CAD lab-developed blood test for aiding the assessment of obstructive coronary artery disease (CAD). Under a multi-year agreement, clinicians will be able to order blood draws on patients for testing through Quest's approximately 2,200 patient service centers and 4,000 phlebotomists in physician offices in the United States. Samples will be forwarded to CardioDx's CLIA-certified laboratory (in Redwood City, Calif.) for testing.

CardioDx, Inc. Announces Positive Results from Clinical Utility Study

CardioDx, Inc. announced the publication of a new study examining the effect of the use of an age, sex, and gene expression score on clinical decision-making and the rate of further cardiac evaluation in symptomatic female patients in the outpatient setting. The study examined the use of the Corus CAD test, a blood test which incorporates age, sex, and gene expression, in 320 women presenting with stable symptoms suggestive of obstructive coronary artery disease (CAD). The study indicated that women with low Corus CAD test scores (=15) were significantly less likely to be referred for further cardiac evaluation (OR 0.013, p<0.0001) by their primary care clinicians within 45 days of follow-up. Only 4% of women (10/248) with low Corus CAD test scores received further testing for obstructive CAD. The Corus CAD test is the first and only commercially available blood-based test incorporating age, sex, and gene expression measurements that provides a current-state assessment of obstructive CAD in non- diabetic patients presenting with non-acute typical or atypical symptoms. The study included 320 women presenting to 16 primary care providers across 9 practice sites and 6 states. The mean Corus CAD test score was 10.3±8.2, with a range of 1 (corresponding to a 1% likelihood of obstructive CAD) to 38 (corresponding to a 62% likelihood of obstructive CAD). Overall, 77.5% of women (248/320) had low Corus CAD test scores. The referral rate for further cardiac evaluation was 4% (10/248) among women with low Corus CAD test scores versus 83.3% (60/72) among women with elevated scores (p<0.0001).

CardioDx, Inc. Announces the Results of Study Demonstrating the Benefits of the Corus Cad Gene Expression Test

CardioDx, Inc. announced the presentation of the study. The study evaluated the clinical utility of the Corus CAD blood-based gene expression test in the assessment of 518 African American patients presenting with symptoms suggestive of obstructive coronary artery disease (CAD) in a primary care setting. The results demonstrate the impact of Corus CAD score on clinician decision-making: Patients with low-Corus CAD scores (= 15) had a 95% decreased rate of referral for advanced cardiac testing compared to patients with elevated (> 15) Corus CAD scores (8/214 vs. 227/304). By ruling out obstructive CAD early in the work-up, the Corus CAD test was able to help clinicians avoid unnecessary referrals to cardiology or advanced cardiac testing when their patients' symptoms are due to non-cardiac causes. Corus CAD is the first and only commercially available blood-based test incorporating age, sex, and gene expression measurements that provides a current-state assessment of obstructive CAD in non-diabetic patients presenting with non-acute typical or atypical symptoms. The results of the gene expression measurements are combined with the patient's age and sex in an algorithm that delivers a score representing the likelihood of obstructive CAD. With a 96% negative predictive value, Corus CAD can help clinicians accurately rule out obstructive CAD as the source of their patients' symptoms, so that they may investigate other non-cardiac causes. Of the 518 patients enrolled in the study, 41% (n=214) had a low Corus CAD score, demonstrating that the test has high relevance to clinical practice for ruling out obstructive CAD in a significant number of patients in everyday practice. The authors concluded that Corus CAD improved care for those patients with a low score by avoiding unnecessary, and potentially invasive, advanced diagnostic testing.

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