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August 28, 2015 7:13 PM ET


Company Overview of MyoKardia, Inc.

Company Overview

MyoKardia, Inc. develops a pipeline of small molecule therapeutics that addresses clinical needs for patients with genetic heart diseases. The company was founded in 2012 and is based in South San Francisco, California.

400 East Jamie Court

Suite 102

South San Francisco, CA 94080

United States

Founded in 2012



Key Executives for MyoKardia, Inc.

Chief Executive Officer and Director
Age: 73
Compensation as of Fiscal Year 2015.

MyoKardia, Inc. Key Developments

MyoKardia Announces Initiation of Phase 1 Clinical Study of MYK-461 for Hypertrophic Cardiomyopathy

MyoKardia, Inc. announced it has initiated dosing in a Phase 1 clinical trial of MYK-461. MYK-461 is the first ever therapy designed to target the underlying cause of hypertrophic cardiomyopathy (HCM), the most common heritable cardiovascular disease. Patients with HCM are born with a mutation that causes over-contraction of the heart muscle cells, leading to thickening and stiffening of the heart muscle. Patients with HCM live with often debilitating disease symptoms including shortness of breath, chest pain and fainting spells. Complications of HCM include progressive heart failure, abnormal heart rhythms, stroke and sudden cardiac death. MyoKardia is developing a portfolio of potential treatments for HCM, each of which is designed to specifically target one of the underlying molecular mechanisms causing the disease. MYK-461 is the first potential treatment in MyoKardiaâ s HCM portfolio to enter clinical development. MYK-461 has been designed to correct one of the most common molecular mechanisms causing HCM, and the clinical program will evaluate patients whose disease is caused by this specific mechanism, as identified by genetic screening. In conjunction with the initiation of MYK-461â s Phase 1 study, the company also announced the expansion of its management team with the appointment of Ingrid Boyes to senior vice president, human resources and Steven Chan to vice president, corporate controller.

MyoKardia, Inc. Presents at SunTrust Robinson Humphrey Biotechnology and Pharmaceutical One-on-One Orphan Drug Day, Feb-23-2015

MyoKardia, Inc. Presents at SunTrust Robinson Humphrey Biotechnology and Pharmaceutical One-on-One Orphan Drug Day, Feb-23-2015 . Venue: JW Marriott Essex House, 160 Central Park South, b/w 6th & 7th Avenue, New York, New York, United States.

MyoKardia, Inc. Presents at 33rd Annual J.P. Morgan Healthcare Conference, Jan-13-2015 03:30 PM

MyoKardia, Inc. Presents at 33rd Annual J.P. Morgan Healthcare Conference, Jan-13-2015 03:30 PM. Venue: Westin St. Francis Hotel, San Francisco, California, United States. Speakers: Tassos Gianakakos, Chief Executive Officer and Director.

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