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September 01, 2015 12:18 AM ET


Company Overview of BioMotiv, LLC

Company Overview

BioMotiv, LLC discovers and develops small molecules, antibodies, proteins, cells, and nucleotides based therapeutics for development of new medicines. BioMotiv, LLC was formerly known as BIOU, LLC. The company was incorporated in 2010 and is based in Cleveland, Ohio.

20600 Chagrin Boulevard

Suite 210

Cleveland, OH 44122

United States

Founded in 2010



Key Executives for BioMotiv, LLC

Chief Executive Officer and Member of Board of Managers
Age: 43
Senior Vice President
Vice President of Business Development
Chief Scientific Officer, Chairman of Advisory Board and Member of Board of Managers
Age: 66
Compensation as of Fiscal Year 2015.

BioMotiv, LLC Key Developments

BioMotiv, LLC Presents at Bio-Trinity, May-11-2015 through May-13-2015

BioMotiv, LLC Presents at Bio-Trinity, May-11-2015 through May-13-2015. Venue: Novotel London West, 1 Shortlands, London W6 8DR, United Kingdom. Presentation Date & Speakers: May-12-2015, Davidson Ateh, CEO. May-13-2015, Mark Payton.

BioMotiv, University of California San Francisco and University of Washington Announces Formation of Optikira

BioMotiv, the University of California San Francisco and University of Washington are announcing the formation of OptiKira, a platform company that will develop small molecule therapeutics that prevent cell death in pathologies caused by misfolded or unfolded proteins. OptiKira is based on intellectual property exclusively licensed from UCSF and University of Washington. The project was initiated at UCSF and the University of Washington by scientific founders Scott Oakes, MD, Associate Professor of Pathology at UCSF, Feroz Papa, MD, PhD, Associate Professor of Medicine at UCSF, Bradley Backes, PhD, Associate Professor of Medicine at UCSF, and Dustin Maly, PhD, Associate Professor in Chemistry at University of Washington. Dr. Oakes and Dr. Papa are members of the first class of Harrington Scholar-Innovators. Extensive research by the Founders has helped define the biological pathway leading to progressive cell death which characterizes diseases such as retinitis pigmentosa, diabetes, and amyotrophic lateral sclerosis (ALS). They have found that the Unfolded Protein Response (UPR), a mechanism by which the cell deals with functionally abnormal proteins, has an important housekeeping role in cell metabolism. However when overloaded, the 'terminal UPR' results in the accumulation of excessive unfolded proteins and cellular death. The team has synthesized inhibitors of IRE1a to prevent the activation of the terminal UPR, while not disrupting the housekeeping role of the enzyme. They have demonstrated that inhibitors of IRE1a, which they have named kinase-inhibiting RNase attenuators (KIRAs), protect cells from degeneration in preclinical models of retinitis pigmentosa and diabetes.

BioMotiv, LLC Presents at Life Sciences Summit 2014, Oct-29-2014 09:00 AM

BioMotiv, LLC Presents at Life Sciences Summit 2014, Oct-29-2014 09:00 AM. Venue: 10 on the Park at Time Warner Center, 60 Columbus Circle, 10th Floor, New York, NY 10019, United States. Speakers: Terry C. Vance, Chief Business Officer.

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