September 25, 2016 10:30 PM ET


Company Overview of SanBio, Inc.

Company Overview

SanBio, Inc. develops regenerative therapies for neurological disorders. Its product pipeline includes SB623 that reverses neural damages, as well as restores functions to damaged neurons associated with strokes, traumatic brain injuries, retinal diseases, and Parkinson's diseases; and SB618 for the treatment of neuron inflammatory injury conditions (multiple sclerosis and spinal cord injuries). The company was founded in 2001 and is based in Mountain View, California. SanBio, Inc. operates as a subsidiary of SanBio Company Limited.

231 South Whisman Road

Mountain View, CA 94041-1522

United States

Founded in 2001





Key Executives for SanBio, Inc.

Co-Founder, Chairman and Co- Chief Executive Officer
Age: 49
Co-Founder, Co- Chief Executive Officer and Director
Age: 49
Senior Vice President of Production Development
Chief Medical Officer and Head of Research
Senior Vice President of Manufacturing
Compensation as of Fiscal Year 2016.

SanBio, Inc. Key Developments

SanBio, Inc. Appoints Greg Gillas as Senior Vice President of Human Resources and Corporate Services

SanBio, Inc. announced the appointment of Greg Gillas as Senior Vice President of Human Resources and Corporate Services. In this role, Greg will be responsible for human resources globally, and information technology and corporate services in the U.S. Mr. Gillas is an industry veteran with more than 20 years of human resources experience in public companies. He most recently served as the Vice President of Compensation and Benefits at AMD. Mr. Gillas assumed his position at SanBio on August 29.

Sanbio, Inc. Announces Randomization of First Patient in STEMTRA Phase 2 Clinical Trial Study for Traumatic Brain Injury

SanBio, Inc. announced the randomization of the first patient in the STEMTRA Phase 2 clinical trial study for traumatic brain injury. The trial is enrolling patients in both the United States and Japan, and the first patient was randomized at Emory University Hospital in Atlanta, GA. The STEMTRA “Stem cell therapy for traumatic brain injury” trial will examine the effects of SB623 stem cell treatment in patients with chronic motor deficits resulting from traumatic brain injury. SB623 cells, SanBio’s proprietary product, are modified allogeneic mesenchymal stem cells, derived from the bone marrow of healthy human adult donors. When administered into neural tissue, SB623 cells appear to promote recovery from injury by triggering the brain’s natural regenerative ability. Traumatic brain injuries can be caused by a wide range of events, including car accidents, falls, firearm mishaps, and battlefield injuries. These events often result in permanent damage, including significant motor deficits; leaving more than 5.3 million people living with disabilities in the United States alone. The STEMTRA trial follows a Phase 1/2a clinical trial in patients with chronic motor deficit secondary to ischemic stroke, which showed statistically significant improvements in motor function following implantation of the modified stem cells. The STEMTRA study will evaluate the efficacy, safety and tolerability of the SB623 cell treatment and administration process in patients with traumatic brain injuries. Patients must be at least 12 months post injury. The study will be conducted across approximately 25 clinical trial sites throughout the United States and five sites in Japan. Total enrollment is expected to reach 52 patients in total.

SanBio, Inc. Presents Interim Results of Chronic Stroke Phase 1/2a Clinical Trial at International Society of Stem Cell Research Annual Meeting

SanBio, Inc. presented the 12-month interim results of a Phase 1/2a clinical trial for the treatment of chronic motor deficits secondary to stroke at the International Society of Stem Cell Research Meeting in San Francisco. Preliminary results suggest that the company's stem cell treatment, SB623, is generally safe and well-tolerated, and may have the ability to improve motor function in patients six months to five years following an ischemic stroke. The trial was the first intracerebral stem cell transplant study for stroke in North America. It was an open-label, single-arm, dose escalation study of 18 patients with chronic motor deficits present for at least six months following an ischemic stroke. Patients received injections of SB623 cells modified allogeneic mesenchymal stem cells derived from the bone marrow of healthy human adult donors which promote recovery from injury when administered into neural tissue by triggering the brain's natural regenerative ability. The data demonstrated statistically significant improvements in motor function based on the European Stroke Scale, National Institutes of Health Stroke Scale, the Fugl-Meyer total score and the Fugl-Meyer motor function total score for all sixteen patients who completed follow-up. SanBio has followed all patients for 24 months following the procedure, and these results will be reported later this year. Based on the encouraging results of this Phase 1/2a study, SanBio and its joint development partner in North America, Sumitomo Dainippon Pharma Co. Ltd., began a Phase 2b controlled clinical trial to further investigate SB623 for the treatment of chronic motor deficits secondary to ischemic stroke. SanBio also began a Phase 2 clinical trial of SB623 for traumatic brain injury in 2015.

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