October 22, 2016 1:07 AM ET

Life Sciences Tools and Services

Company Overview of Pacific Biosciences of California, Inc.

Company Overview

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing systems to resolve genetically complex problems. The company’s single molecule real-time (SMRT) sequencing technology enables single molecule real-time detection of biological processes. It offers PacBio RS II and Sequel Systems that conducts, monitors, and analyzes biochemical sequencing reactions. The company also provides consumable products, including sealed and packaged SMRT cells, as well as various reagent kits, such as template preparation, binding, and sequencing kits to run the PacBio RS II or Sequel System. Its customers include research institutions; commercial laboratories; genome centers; cli...

1380 Willow Road

Menlo Park, CA 94025

United States

Founded in 2000

394 Employees



Key Executives for Pacific Biosciences of California, Inc.

Executive Chairman, Chief Executive Officer and President
Age: 67
Total Annual Compensation: $1.0
Chief Financial Officer, Principal Accounting Officer and Executive Vice President
Age: 62
Total Annual Compensation: $1.0
Senior Vice President of Market Development
Age: 57
Total Annual Compensation: $424.3K
Senior Vice President of Research and Development
Age: 65
Total Annual Compensation: $424.3K
Compensation as of Fiscal Year 2015.

Pacific Biosciences of California, Inc. Key Developments

Pacific Biosciences of California, Inc. to Introduce New Sequel System Chemistry Release (1.2.1)

Pacific Biosciences of California, Inc. to introduce a new Sequel System chemistry release (1.2.1) that enables loading of sequencing libraries with average insert size of 20-30 kb onto Sequel SMRT Cells with a 50-fold reduction of DNA input requirement compared to previous Sequel chemistry. Internal results using the new Sequel System chemistry, which have been replicated at several beta sites, have shown mapped read-length N50s of >16 kb and output of >5 Gb per Sequel SMRT Cell. Additional details will be discussed during the company’s ASHG workshop (more details on the event below), and commercial availability is expected starting October 25, 2016.

Dovetail Genomics™ LLC Adds Pacific Biosciences of California, Inc.'s PacBio® SMRT® Sequencing and Assembly to Its Services Menu

Pacific Biosciences of California, Inc. and Dovetail Genomics™ LLC announced that Dovetail has added PacBio® SMRT® sequencing and de novo assembly options to its menu of genome assembly services. The companies also announced their signing of a co-marketing agreement under which the new service offerings will be jointly promoted. PacBio SMRT Sequencing delivers long read lengths with high consensus accuracy and uniform coverage, allowing scientists to go beyond fragmented draft genomes and generate the most comprehensive de novo assemblies. Dovetail found through its services that its approach to scaffolding with Chicago™ libraries and its HiRise™ scaffolding pipeline are highly complementary to PacBio-based assemblies. This new offering is especially valuable to scientists working on highly repetitive, polyploid genomes that are challenging to resolve with short-read sequencing alone.

Pacific Biosciences of California, Inc. Releases New Software and Chemistry for Sequel System

Pacific Biosciences of California, Inc. announced it has released a set of key updates for the Sequel™ System, the company’s latest product based on its Single Molecule, Real-Time (SMRT®) Sequencing technology. The new release provides performance improvements via updated sequencing chemistry, optimized sample clean-up protocols, and associated software that together further improve read lengths, throughput and accuracy of the system. In addition, as customers upgrade their Sequel Systems to the new software and chemistry, they will no longer be subject to the supply constraints for SMRT Cells that were in effect earlier this year.

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