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July 30, 2015 5:21 PM ET

Healthcare Equipment and Supplies

Company Overview of CardioKinetix, Inc.

Company Overview

CardioKinetix, Inc. operates as a medical device company that develops catheter-based treatment devices to treat congestive heart failures resulting from a heart attack in patients. The company offers a partitioning device deployed within the left ventricle (for ischemic left sided heart failure patients) that partitions damaged muscles by isolating the non-functional muscle segment from the functional segment; MRI-related heating products; parachute delivery components; percutaneous ventricular restoration therapies; and ventricular restoration products. It serves customers worldwide. The company was incorporated in 2002 and is headquartered in Menlo Park, California.

925 Hamilton Avenue

Menlo Park, CA 94025

United States

Founded in 2002

Phone:

650-364-7016

Fax:

650-364-7038

Key Executives for CardioKinetix, Inc.

Chief Executive Officer, President and Director
Age: 49
Chief Financial Officer
Vice President of Operations
Age: 52
Vice President of Technology, Therapy and Clinical
Compensation as of Fiscal Year 2015.

CardioKinetix, Inc. Key Developments

CardioKinetix Inc. Completes Enrollment in Chinese Trial of First-of-Its-Kind Parachute Device for Treatment of Heart Failure

CardioKinetix Inc. announced the completion of enrollment in PARACHUTE China, a multi-center trial to evaluate the minimally invasive Parachute® Ventricular Partitioning Device for the treatment of heart failure. PARACHUTE China enrolled NYHA II to ambulatory IV ischemic heart failure patients with ejection fraction 15-40% to support the regulatory submission for the Parachute device to the China Food and Drug Administration (CFDA). The primary endpoint of the study is reduction in left ventricle end systolic volume index (LVESVi) at three months, which will be analyzed at an echocardiography core lab, Yale Cardiovascular Research Group.

CardioKinetix, Inc. Releases Results of a Pooled Analysis Study of Parachute Ventricular Partitioning Device

CardioKinetix Inc. announced results of a pooled analysis study of the first-of-its-kind catheter-based Parachute(R) Ventricular Partitioning Device. Twelve-month clinical data from PARACHUTE III, a study of 100 post-market European patients with ischemic heart failure treated consecutively between 2011 and 2013, were presented at the 2014 TCT Conference in Washington, D.C., by Ulrich Schäfer, M.D., cardiology director of the Structural Heart Division at the Heart Center at the University Medical Center Hamburg-Eppendorf, and at the 2014 HFSA Conference in Las Vegas, Nev., by William Abraham, M.D., professor of internal medicine and director of the Division of Cardiovascular Medicine at Ohio State University Medical Center. Parachute had a very high procedural success rate of 97% (97/100). The twelve-month highlights from the data include: Primary safety endpoint yielded a low 7% rate of device- or procedure-related MACCE. Sustained reduction of left ventricle volumes (p < 0.0001) resulting in significant improvements in systolic function and a significant reduction in left atrial volume (p < 0.05) reflected improved diastolic function. NYHA functional class improved or maintained in 80% of patients. Six-minute walk distance improved at follow-up (p < 0.01), with 46% of patients walking an additional 20 meters or more. Rates of death and the combined endpoint of death and repeat hospitalization for heart failure were 9.5% and 26.0%, respectively.

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