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November 29, 2015 12:59 AM ET


Company Overview of Thrombolytic Science International, LLC

Company Overview

Thrombolytic Science International, LLC engages in the development of a thrombolytic product. It provides M5, a thrombolytic drug that is used for percutaneous coronary intervention and ischemic stroke. The company was incorporated in 2004 and is based in Cambridge, Massachusetts.

763D Concord Avenue

Cambridge, MA 02138

United States

Founded in 2004





Key Executives for Thrombolytic Science International, LLC

Co-Founder, Chief Executive Officer and President
Co-Founder and Scientific Director
Compensation as of Fiscal Year 2015.

Thrombolytic Science International, LLC Key Developments

Thrombolytic Science, LLC enters into agreement with National Institutes of Health to Test a Novel Thrombolytic Regimen for the Treatment of Acute Ischemic Stroke in Phase IIa Clinical Trial

Thrombolytic Science, LLC (TSI) announced that is has entered into an agreement with the National Institutes of Health (NIH). Under a Cooperative Research and Development Agreement (CRADA) with the National Institute of Neurological Disorders and Stroke (NINDS), and upon receipt of an IND from the FDA, TSI will work with leading researchers at the NINDS /Intramural Stroke Program to test the safety of dual thrombolytic therapy using tissue plasminogen activator and an improved version of prourokinase (HisproUK) in patients suffering from acute ischemic stroke (AIS). TSI will provide the study drug while NINDS will conduct a phase IIa trial. The multicenter trial will be performed in a population of AIS patients recruited by the NIH intramural stroke program, using a combined clinical and MRI-guided approach to patient selection.

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