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November 29, 2015 12:18 AM ET

Life Sciences Tools and Services

Company Overview of Aragen Bioscience, Inc.

Company Overview

Aragen Bioscience, Inc. provides preclinical contract research and development services. The company specializes in recombinant cell line and hybridoma development, cell culture and protein purification process development and production, primary and immortalized cell-based assays, in vivo models of human disease and custom immunological services for the pharmaceutical and biotech industries. Its cell line development services include molecular biology and cell culture, cell line productivity and stability studies, cell culture, and analytical services; molecular biology services comprise isolation of nucleic acids, RT-PCR detection methods and generation of cDNA, primer design, vector const...

380 Woodview Avenue

Morgan Hill, CA 95037

United States

Founded in 2006





Key Executives for Aragen Bioscience, Inc.

Chief Executive Officer and President
Chief Technology Officer and Vice President
Vice President of Laboratory Services
Director of Pre-Clinical Research Services
Director of Cell Biology
Compensation as of Fiscal Year 2015.

Aragen Bioscience, Inc. Key Developments

Aragen Bioscience, Inc. and Transposagen Biopharmaceuticals, Inc. Partner to Launch FUT8 Knockout CHO DG44 Cell Line Development Services

Aragen Bioscience, Inc. and Transposagen Biopharmaceuticals, Inc. has developed a FUT8 knockout CHO DG44 host cell line. The elimination of the FUT8 gene results in afucosylated protein products. When applied to antibodies, the result is increased ADCC activity, and improved efficacy. Aragen Bioscience, is now offering protein expression and cell line development services with this cell line for products to be used for research purposes. The launch of a FUT8 knockout CHO DG44 host cell line for the development of high-expressing cell lines suitable for GMP manufacturing is expected in the second half of this year. Transposagen is now offering custom gene editing services using the FUT8 knockout CHO DG44 host cell line. Examples of custom services would be to rapidly and stably integrate a customer™s transgene into the cell line using the piggyBacTM DNA Modification System or to further genetically modify the cell line to enhance protein production. Transposagen will also offer gene editing kits containing the cell line and Transposagen™ unique technologies, including Footprint-FreeTM Gene Editing, to create disease-specific cell lines and XTNTM TALEN or NextGENTM CRISPRs to create additional gene knockouts and knock-ins. Industry and academic researchers will be able to create their own engineered cell lines or outsource the work, providing them with access to manufacturing services and a clear path to commercialization through partnerships with Transposagen and Aragen Bioscience.

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