The Translational Genomics Research Institute develops earlier diagnostics and treatments. It develops diagnostics, prognostics, and therapies for cancer, neurological disorders, diabetes, and other complex diseases. The company also provides bio4d to offer tools for managing various aspects of the biospecimen lifecycle, including related data enabling clinical genomics data warehouse capabilities for data mining and integrative analysis for the discovery or validation of biomarkers, diagnostics, and therapeutics. In addition, The Translational Genomics Research Institute offers genome technology and core services; genome technology for performing contemporary genetic analysis to benefit the...
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Spectrum Health Collaborates with Dell and Translational Genomics Research Institute to Expand International Pediatric Cancer Research to Lebanon
Mar 18 15
Spectrum Health announced its engagement in international pediatric cancer research. Together with Helen DeVos Children's Hospital, Dell and the Translational Genomics Research Institute, Spectrum Health will bring a personalized medicine clinical trial to children fighting pediatric cancers in Lebanon. Led by Giselle Sholler, MD, MSC, director of pediatric oncology research, Helen DeVos Children's Hospital and Jeffery Trent, PhD, FACMG, president and research director, TGen, the trial focuses on identifying drug treatments tailored, or personalized, to the specific genomic changes within the tumors of children with aggressive cancers. Also referred to as precision medicine, this type of research aims to customize drug treatment plans to the unique genetic makeup of an individual's tumor cell. Highly advanced computations provide explicitly detailed genomic information. In the trial, researchers study tumor biopsies using DNA and RNA sequencing performed at TGen. The data is then shared with Spectrum Health and analyzed using Dell computer power and complex algorithms constructed by the research team. An international group of physicians and researchers collaborate on the findings - through a customized online virtual meeting space - and design recommended treatment plans targeted for each patient's tumor. Ray Saab, MD, pediatric oncologist, American University of Beirut, Lebanon, is the physician investigator for the Lebanon arm of the NMTRC precision medicine trial.