NorthShore University HealthSystem operates hospitals and medical group offices. It offers treatment for alcohol addictions and substance abuses, allergies, asthma and immunology, arthritis, cancer, cardiovascular, diabetes, psychiatry and behavioral sciences, and others. The company also provides services in the areas of dentistry, dermatology, emergency medicine, endocrinology, family medicine, gastroenterology, general surgery, home health, hospice, integrative medicine, internal medicine, interventional radiology, medical genetics, nephrology, neurology, nuclear medicine, obstetrics and gynecology, ophthalmology, orthopedic, otolaryngology, plastic surgery, vascular surgery, and women's ...
2650 Ridge Avenue
Evanston, IL 60201
Founded in 1891
NorthShore University HealthSystem Announces Partnership with Mayo Clinic to Study Genomics of Antiplatelet Heart Medication
Nov 19 13
NorthShore University HealthSystem is partnering with Mayo Clinic as the only site in Illinois participating in the Tailored Antiplatelet Therapy to Lessen Outcomes after Percutaneous Coronary Intervention (TAILOR-PCI) Study. The study examines whether prescribing heart medication based on a patient’s CYP2C19 genotype will help prevent heart attack, stroke, unstable angina, and cardiovascular death in patients who undergo percutaneous coronary intervention, commonly called angioplasty. Antiplatelet medication reduces the risk of heart attack, unstable angina, stroke, and cardiovascular death after stent placement by reducing the possibility of blood clots around the surgical site. Plavix, however, remains ineffective until the liver enzyme CYP2C19 metabolizes the drug into its active form. Some alternative medications, including Brilinta (ticagrelor), do not require activation through the same genetic pathway. Another additional benefit of the study will be creation of a coronary artery disease biobank containing DNA samples from the study’s 5,300 participants. Researchers at NorthShore and other participating sites can mine these samples and use genomic sequencing technologies to help further medicine’s understanding of the origins of and risk factors for coronary heart disease.