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Last $5.79 USD
Change Today +0.08 / 1.40%
Volume 997.2K
PGNX On Other Exchanges
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As of 8:10 PM 03/27/15 All times are local (Market data is delayed by at least 15 minutes).

progenics pharmaceuticals (PGNX) Key Developments

Progenics Pharmaceuticals, Inc. Announces Unaudited Consolidated Earnings Results for the Fourth Quarter and Year Ended December 31, 2014; Reports Impairment Charges for the Fourth Quarter of 2014

Progenics Pharmaceuticals, Inc. announced unaudited consolidated earnings results for the fourth quarter and year ended December 31, 2014. The company reported Fourth quarter revenue resulted in a loss of $0.6 million, primarily from RELISTOR royalty losses due to Salix's plan to accelerate the reduction of wholesaler inventory levels and substantially cease all sales efforts to wholesalers in the fourth quarter of 2014. This compares to revenues of $3.0 million due to RELISTOR royalty income in the fourth quarter of 2013. Operating loss was $12,954,000 against $8,923,000 a year ago. Net loss before income tax benefit was $12,940,000 against $8,913,000 a year ago. Net loss was $12,179,000 or $0.18 per basic and diluted share against $8,551,000 or $0.14 per basic and diluted share a year ago. For the year, the company reported total revenue of $44,377,000 against $7,862,000 a year ago. Operating income was $3,370,000 against operating loss of $42,980,000 a year ago. Net income before income tax benefit was $3,421,000 against net loss before income tax benefit of $42,934,000 a year ago. Net income was $4,410,000 or $0.06 per basic and diluted share against net loss of $42,572,000 or $0.76 per basic and diluted share a year ago. Full year 2014 revenue was up from the prior year, reflecting an increase in collaboration revenue, primarily resulting from the recognition of milestone from Salix, partially offset by decrease in RELISTOR royalty income, compared to 2013. For the quarter, the company reported intangible impairment charges of $2,100,000.

Progenics Pharmaceuticals, Inc., Q4 2014 Earnings Call, Mar 16, 2015

Progenics Pharmaceuticals, Inc., Q4 2014 Earnings Call, Mar 16, 2015

Progenics Pharmaceuticals Presents Positive Phase 2 Data for PSMA

Progenics Pharmaceuticals, Inc. announced full results from its Phase 2 clinical study of PSMA ADC in patients with metastatic castration-resistant prostate cancer (mCRPC), including new data from the recently completed chemo-na ve cohort. The data was presented in a poster session and was also selected for inclusion in the ASCO GU Audio Poster Tour at the American Society of Clinical Oncology Genitourinary Cancers (ASCO GU) Symposium, taking place from February 26 28, 2015 in Orlando, Florida. The Phase 2 trial assessed the anti-tumor activity and tolerability of PSMA ADC, an antibody drug conjugate, in both taxane-experienced and chemo-na ve patients that had progressed following treatment with abiraterone and/or enzalutamide. In the chemo-na ve cohort, treatment with PSMA ADC reduced tumor size and levels of PSA and CTCs (circulating tumor cells) evidencing strong anti-tumor activity. Among these chemo-na ve patients, one (3%) had a complete radiological response, four (14%) had a partial radiological response, 22 (76%) showed stable disease, and two (7%) experienced progressive disease. The study enrolled 119 patients with mCRPC that had progressed following treatment with abiraterone and/or enzalutamide, including 84 taxane-experienced patients and 35 chemo-na ve patients. Patients in the trial received PSMA ADC 2.5mg/kg or 2.3 mg/kg intravenously three times weekly for up to 8 cycles. Safety, antitumor activity, and exploratory biomarkers were assessed.

Progenics Pharmaceuticals, Inc. Presents at RBC Capital Markets Healthcare Conference 2015, Feb-24-2015 02:05 PM

Progenics Pharmaceuticals, Inc. Presents at RBC Capital Markets Healthcare Conference 2015, Feb-24-2015 02:05 PM. Venue: The New York Palace Hotel, New York, New York, United States. Speakers: Mark R. Baker, Chief Executive Officer, Director and Member of Science & Strategy Committee.

Progenics Pharmaceuticals Relaunches Pivotal Trial of AZEDRA in Pheochromocytoma

Progenics Pharmaceuticals, Inc. announced that it has dosed the first subject in the resumed pivotal Phase 2 clinical study of Azedra in patients with malignant pheochromocytoma and paraganglioma. The trial is being conducted under a Special Protocol Assessment (SPA) with the U.S. Food and Drug Administration (FDA). The study is designed to evaluate the efficacy and safety of the administration of two therapeutic doses of Azedra in patients with malignant relapsed/refractory pheochromocytoma or paraganglioma, ultra-orphan cancers with limited treatment options. The primary objective of the study is to determine the clinical benefit of Azedra based on the proportion of study participants with a reduction of all antihypertensive medication by at least 50% for at least six months. The SPA requires that 25% of 58 evaluable patients achieve the primary endpoint. In late 2010, MIP suspended enrollment in the trial to seek additional funding. The trial has now resumed to fulfill enrollment requirements under the SPA. The trial has treated 41 patients and 32% of those patients have achieved the primary endpoint. The most common adverse events observed have been gastroenterological and hematologic disorders.

 

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