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Pharmaxis’s Bronchitol Wins U.K. Cost Agency’s Backing

Pharmaxis Ltd.’s Bronchitol won the backing of the U.K.’s health-cost regulator for use in some patients with cystic fibrosis, a rare genetic illness.

The drug may be used for adults who can’t use other treatments and whose lung function is rapidly declining, the London-based National Institute for Health and Clinical Excellence, known as NICE, said in a statement on the final draft recommendations. The agency reversed a decision from June, in which the agency said it couldn’t back the drug because of “gaps and uncertainties in the evidence on its effectiveness.”

The agency advises the National Health Service on which treatments represent value for money. Final guidance on Bronchitol, also known as mannitol, is expected to be published in November, NICE said.

“Following the helpful responses received during consultation on the draft guidance, the committee concluded that mannitol was a good use of NHS resources when treatment was offered to those who cannot use hypertonic saline or rhDNase and whose lung function is rapidly declining,” the agency said.

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