Bloomberg Anywhere Remote Login Bloomberg Terminal Demo Request


Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world.


Financial Products

Enterprise Products


Customer Support

  • Americas

    +1 212 318 2000

  • Europe, Middle East, & Africa

    +44 20 7330 7500

  • Asia Pacific

    +65 6212 1000


Industry Products

Media Services

Follow Us

Roche to Seek Approval for Breast Cancer Treatment by Year End

Roche Holding AG will seek regulatory approval this year for a breast cancer treatment that the company said extended patients’ lives without their disease getting worse in a clinical trial.

The treatment, pertuzumab, when combined with chemotherapy and Roche’s Herceptin, helped patients with an aggressive form of breast cancer more than chemotherapy and Herceptin alone, Roche said today in a statement, citing the results of a late-stage clinical trial called Cleopatra.

Pertuzumab, like Herceptin, works by neutralizing the so-called HER-2 protein linked to tumor growth. Both drugs were developed by U.S. biotechnology company Genentech Inc., which Basel, Switzerland-based Roche fully acquired in 2009 for $46.8 billion. Roche is the world’s biggest maker of cancer medicines.

“These results with pertuzumab combined with Herceptin and docetaxel are very encouraging,” Hal Barron, Roche’s head of global product development, said in the statement, referring to the type of chemotherapy used in the study. “We plan to submit the study results for global regulatory approval this year.”

Roche may need more information on overall patient survival to win U.S. regulatory approval, Jack Scannell, an analyst at Sanford C. Bernstein in London, said.

“The Food and Drug Administration wonders if a therapy is worth approving if all it can claim is that it slows the rate at which CT and MRI scans get worse,” Scannell wrote today in a note to clients. “The size of pertuzumab’s incremental benefit may also come under scrutiny given the likely cost.”

Roche rose 90 centimes, or 0.7 percent, to 136.8 francs at 11:27 a.m. in Zurich.

Please upgrade your Browser

Your browser is out-of-date. Please download one of these excellent browsers:

Chrome, Firefox, Safari, Opera or Internet Explorer.