Five-time men’s champion Federer, 31, the top seed from Switzerland, won 6-2, 6-3, 6-2 against Bjorn Phau of Germany. Three-time women’s winner Williams, 30, an American seeded fourth this year, defeated Spain’s Maria Jose Martinez Sanchez 6-2, 6-4 at the National Tennis Center in New York.
Tsonga, the men’s fifth seed from France, was upset by Slovakia’s Martin Klizan in the second round for his earliest exit from a Grand Slam tournament since 2007.
Roddick, the last American man to win a major championship, said he’ll retire at the end of the tournament. Roddick, who turned 30 today, has a second-round match tomorrow night.
Roddick, who has won more than $20 million in a career that has included 32 titles, won the U.S. Open in 2003 and lost Wimbledon finals in 2004, 2005 and 2009 to Federer. He also lost the 2006 U.S. Open final to Federer.
“I’ve decided that this is going to be my last tournament,” he said in a news conference a day before facing Australia’s Bernard Tomic. “I just feel like it’s time.”
Tsonga lost 6-4, 1-6, 6-1, 6-3 to the unseeded Klizan, who is ranked 52nd in the world. The 27-year-old Frenchman had reached at least the third round of every major tournament he had played since a first-round loss at the 2007 Australian Open.
Tsonga, a semifinalist the past two years at Wimbledon who has never advanced past the quarterfinals at the U.S. Open, lost seven of 17 service games against his 23-year-old opponent.
“I was not in good shape, I didn’t play good tennis,” Tsonga said in a news conference. “It seemed like I couldn’t hit the ball enough hard to put my opponent out of position.”
A pair of American men joined Klizan in the third round. Mardy Fish, seeded 23rd, came back from a two-set deficit to defeat Nikolay Davydenko of Russia and unseeded Jack Sock, 19, won in straight sets against Flavio Cipolla of Italy.
Also advancing were No. 15 Milos Raonic, 21, of Canada, who had 30 aces against Paul-Henri Mathieu of France, and unseeded American James Blake, 32 -- a straight-set winner against No. 24 Marcel Granollers of Spain.
Sixth-seeded Tomas Berdych of the Czech Republic won 6-1, 6-4, 6-2 against Jurgen Zopp of Estonia. Sam Querrey, an American seeded 27th, also reached the third round with a straight-set victory against Ruben Ramirez Hidalgo of Spain.
Women’s No. 2 seed Agnieszka Radwanska of Poland lost the first set and trailed 3-1 in the second before winning the last 11 games in a 4-6, 6-3, 6-0 defeat of Spain’s Carla Suarez Navarro.
Sloane Stephens, a 19-year-old American, reached the third round for the second straight year with a 5-7, 6-4, 6-2 win against Tatjana Malek of Germany and will face Ana Ivanovic, the 12th seed from Serbia and the 2008 French Open champion, who won 6-2, 6-2 against Sofia Arvidsson of Sweden.
They were joined in the third round by Maria Kirilenko of Russia, the 14th seed, who beat Hungary’s Greta Arn 6-3, 6-2.
Kirilenko, who didn’t face a break point, was watched by her boyfriend, two-time National Hockey League Most Valuable Player Alexander Ovechkin of the Washington Capitals, at Louis Armstrong Stadium.
Venus Williams, a two-time U.S. Open winner, is playing later tonight.
To contact the editor responsible for this story: Michael Sillup at email@example.com