The loss ruined a career-high 12-strikeout performance by the Yankees’ Ivan Nova before the home fans at Yankee Stadium.
Brandon Phillips had a run-scoring single in the first, followed by Chris Heisey’s double in the second to gave the Reds a 2-0 lead.
Russell Martin hit his fourth home run this season in the third inning and Raul Ibanez sent Robinson Cano home with a double in the fourth to tie the game at 2-2.
Votto hit his three-run homer in the fifth, while Jayson Nix hit a home run for the Yankees in the bottom of the inning to put the score at 5-3.
Philips scored on Mike Costanzo’s sacrifice fly in the eighth to give the Reds a 6-3 lead. Nick Swisher and Nix each drove in Yankee runs in the ninth.
Homer Bailey (2-3) allowed three runs on seven hits while striking out seven in 6 1/3 innings. Jose Arredondo got his first save after pitching a perfect 2/3 inning.
Nova (4-2) gave up five runs on seven hits in six innings for the Yankees (21-19), who are in fourth place in the five- team American League East, 5 ½ games behind the Baltimore Orioles.
The Reds (20-19) are in second place, 1.5 games behind the St. Louis Cardinals in the National League Central division.
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