Roche Drugs Promising in Schizophrenia, Blood Cancer

Roche Holding AG (ROG)’s experimental schizophrenia medicine RG1678 reduced symptoms, and a new treatment for a kind of blood cancer “showed promising response rates,” mid-stage studies found.

The schizophrenia drug was also linked to beneficial changes in patients’ personal and social functioning, the Basel-based company said today in a statement.

As many as 55 percent of patients responded to treatment with the experimental compound GA101, which is being tested for use in people with difficult-to-treat Non-Hodgkin’s lymphoma who have failed multiple previous treatments, the company said in a another statement. Roche gained GA101 through its 235-million Swiss franc ($241 million) acquisition in 2005 of Switzerland’s GlycArt. Both RG1678 and GA101 are in the second of three stages of clinical development generally needed to win regulatory approval.

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To contact the editor responsible for this story: Phil Serafino at

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