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Human Genome Skids

Human Genome Science (HGSI) says a Phase II clinical trial of topically administered repifermin in adults with chronic venous ulcers did not meet its targets. UBS Financial sees a buying opportunity. S&P maintains hold.

John Hancock Financial (JHF) is again in advanced stages of negotiations with a potential buyer, according to several executives familiar with those talks, The Boston Globe reported.

Biosite (BSTE) shares fell following a conference call that failed to ease concerns over its Triage BNP (b-type natriuretic peptide) Test. Biosite cut the 2003 guidance on Wednesday, citing a shortfall in sales of the blood test. Deutsche Bank keeps hold.

SCO Group (SCOX) fell on reports that IBM filed new claims against SCO alleging copyright infringement along with previous claims of patent infringement.

McDonald Investments downgraded Wild Oats Market (OATS) to hold from aggressive buy.

Research in Motion (RIMM) posted 10 cents second-quarter adjusted earnings per share (excluding a litigation charge), vs. an 18 cents loss, on a 70% revenue rise. Bear Stearns upgraded to peer perform from underperform. S&P upgraded to accumulate.

Motorola (MOT) may miss a opportunity to sell some of its first camera phones in the U.S. during the key holiday season because of delivery delays, according to The Wall Street Journal . S&P maintains sell.

Kaufman Bros downgraded (FWHT) to hold from buy.

Trimeris (TRMS) sees $9.5 million to $10.5 million third-quarter net revenues from U.S. Fuzeon sales. USB Piper reportedly downgraded to underperform.

Fisher Scientific (FSH) will sell 6.6 million shares to Banc of America.

Nokia (NOK) announced a reorganization to put a greater emphasis on content. It will split into four business groups.

J.P. Morgan upgraded Intel (INTC) to neutral from underweight.

Manugistics (MANU) posted an 11 cents second-quarter loss, vs. a 68 cents loss, (GAAP) as lower operating costs offset a 15% revenue drop. The company sees breakeven third-quarter adjusted net income, and further improvement in the fourth quarter. Bear Stearns upgraded to peer perform.

CS First Boston downgraded Novellus Systems (NVLS) to neutral from outperform.

IMC Global (IGL) announced that John Ferguson, president and chief operating officer has resigned, effective Sept. 23. IMC says it has no current plans to fill the chief operating officer role.

Avaya (AV) agreed to acquire Vista's Professional Services and Managed Service business units, as well as purchase selected service delivery technology assets.

Solectron (SLR) posted a 22 cents fourth-quarter loss, vs. a $3.21 loss (GAAP), despite a 3.2% total sales fall. Solectron sees $2.7 billion to $3.1 billion in first-quarter sales, and a 1 cent to 4 cents pro forma loss. S&P reiterates hold.

Vans (VANS) posted 64 cents, vs. 31 cents, first-quarter earnings per share from continuing operations (GAAP) on a 14% same-store sales rise. The footwear retailer sees 25 cents to 35 cents fiscal 2004 earnings per share (GAAP).

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