Canada's benchmark S&P/TSX fell 61.88 points to 7,398.83.
European markets ended with gains. In London, the Financial Times-Stock Exchange 100 index closed higher by 6.60 points, or 0.13%, to 4,934.80. UK industrial production rose 1.1% in April, the first increase in 8 months. But output was down 4.1% on a year-over-year basis.
In France, the CAC 40 jumped 84.43 points, or 2.1%, to 4,109.37. And in Germany, the DAX Index was up 16.83 points, or 0.37%, to 4,606.09, as German industrial production rose 0.2% in April, bolstering hopes for an economic recovery.
In Asia, the markets finished mixed. The Nikkei gained 79.23 points, or 0.70%, to close at 11,449.44 points as market players determined the slide over the past few days could not be justified in light of increasing signs of economic recovery. But investors were temperate in their enthusiasm amid uncertainties over corporate earnings and accounting.
In Hong Kong, the market fell 73.82 points, or 0.65%, to close at 11,215.02.