Cardica Announces Data Presentation At Amazing Technologies Session Of 14th Annual World Congress Of Endoscopic Surgery

 Cardica Announces Data Presentation At Amazing Technologies Session Of 14th
                 Annual World Congress Of Endoscopic Surgery

-- Results Validate "D" Shape Staple Used in Cardica's MicroCutter XCHANGE® 30
Enables 5-Millimeter and Potentially 3-Millimeter Surgical Stapler --

PR Newswire

REDWOOD CITY, Calif., June 30, 2014

REDWOOD CITY, Calif., June 30, 2014 /PRNewswire/ -- Cardica, Inc. (Nasdaq:
CRDC) today announced that Dr. Stefanos Demertzis, associate professor at the
University of Berne, Switzerland and senior staff cardiac surgeon and deputy
head of the department of cardiac surgery at the Cardiocentro Ticino Lugano,
completed a study that demonstrated that there was no difference in the
chronic healing response between the innovative D-shaped staple design of the
Cardica five-millimeter MicroCutter XCHANGE^® 30 and the B-shaped staple
design used in conventional 12-millimeter surgical staplers.

The results of the study, entitled "Beyond the "B": A New Concept of the
Surgical Staple Enabling Miniature Staplers," were presented by Dr. Lee
Swanstrom, chief innovations officer at the University of Strasbourg's
University Hospitals Institutes, clinical professor of surgery for Oregon
Health and Sciences University and medical director of Cardica, as part of the
Amazing Technologies Session at the 14^th Annual World Congress of Endoscopic
Surgery in Paris, France, a meeting hosted by the European Association for
Endoscopic Surgery (EAES) in conjunction with the SFCE (Societe Francaise de
Chirurgie Endoscopique) and the International Society for Laparoscopic
ColoRectal Surgery (ISLCRS). http://congress.eaes.eu/Home.aspx.

"All current staplers rely on the same staple form—the "B"—which is inherited
from the common paper stapler," commented Dr. Demertzis. "This shape, while
effective, necessitates a large delivery profile of at least 12 millimeters.
Importantly, the D-shaped staple allows for a five millimeter surgical stapler
today, and potentially a further reduction in size to three millimeters in the
future. This is the first major advancement in the size of surgical staplers
in nearly 30 years. With the smaller size of the MicroCutter, the D-staple, as
well as the increased articulation, I believe this device will enable the
advancement of minimally invasive surgery across the world."

The study compared the standard B-form staple, used in conventional
12-millimeter surgical staplers, to the innovative D-shaped staple used in the
Cardica MicroCutter XCHANGE 30, the world's first and only five-millimeter
surgical stapler that articulates to 80 degrees. Chronic histology performed
showed that the D-shaped staple elicited a normal healing response with
minimal inflammation and lack of excessive scar tissue formation. Further,
there was no difference in the chronic healing response between "D" and "B"
shaped staples.

"We are pleased to have the results of this study presented at the prestigious
European Association for Endoscopic Surgery meeting, which brings together the
key opinion leaders in minimally invasive surgery from around the world," said
Bernard A. Hausen, M.D., Ph.D., president and CEO of Cardica. "As the use of
our MicroCutter XCHANGE 30 grows, this study validates the underlying
technology necessary for the miniaturization of stapling devices and
complements the recent selection of our device as a finalist in the Medical
Design Excellence Awards."

About Cardica
Cardicadesigns and manufactures proprietary stapling and anastomotic devices
for laparoscopic and cardiac surgical procedures.Cardica's technology
portfolio is intended to reduce operating time and facilitate
minimally-invasive and robot-assisted surgeries. Cardica's MicroCutter
XCHANGE^® 30, a cartridge-based articulating surgical stapling device with a
five-millimeter shaft diameter, is manufactured and cleared for use in a
variety of gastrointestinal procedures and appendectomies in the United
States, and is marketed for a wide range of surgical procedures in Europe.
Cardicais developing the Cardica^® MicroCutter XCHANGE^® 45, a
cartridge-based microcutter device that is being designed with an
eight-millimeter shaft to be used in a variety of procedures, including
bariatric, colorectal, thoracic and general surgery. The Cardica MicroCutter
XCHANGE 45 product requires 510(k) clearance and CE Mark and is not yet
commercially available in the U.S. or internationally. In addition, Cardica
manufactures and markets its automated anastomosis systems, the C-Port^®
Distal Anastomosis Systems and PAS-Port^® Proximal Anastomosis System for
coronary artery bypass graft (CABG) surgery, and has shipped over 50,000 units
throughout the world.

Forward-Looking Statements
The statement in this press release regarding the belief that the XCHANGE 30
will enable the advancement of minimally invasive surgery across the world is
a "forward-looking statement." There are a number of important factors that
could cause Cardica's results to differ materially from those indicated by
this forward-looking statement, including: that Cardica may not be successful
in its efforts to commercialize the XCHANGE 30 due to unanticipated technical
or other difficulties; that prospective customers may not perceive the
benefits of the XCHANGE 30 to be sufficient to warrant its purchase; that
prospective customers may be constrained by pricing pressures or purchasing
requirements in the hospitals and facilities in which they work, which could
prevent them from purchasing the XCHANGE 30; the 3-mm surgical stapler is in
the very early stages of development, and Cardica may encounter unexpected
difficulties in developing a 3-mm surgical stapler and may determine not to
develop a 3-mm surgical stapler for financial, technical or other reasons; as
well as other risks detailed from time to time in Cardica's reports filed with
the U.S. Securities and Exchange Commission, including its Quarterly Report on
Form 10-Q for the quarter endedMarch 31, 2014, under the caption "Risk
Factors," filed on May 7, 2014. Cardica expressly disclaims any obligation or
undertaking to release publicly any updates or revisions to any
forward-looking statements contained herein. You are encouraged to read
Cardica's reports filed with the U.S. Securities and Exchange Commission,
available at www.sec.gov.

SOURCE Cardica

Contact: Bob Newell, Vice President, Finance and Chief Financial Officer,
(650) 331-7133, investors@cardica.com
 
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