Evidence review shows positive results for Negative Pressure Wound Therapy
(NPWT) on surgical incisions
ST. PETERSBURG, Fla., Jan. 22, 2014
ST. PETERSBURG, Fla., Jan. 22, 2014 /PRNewswire/ --Smith & Nephew (LSE: SN,
NYSE: SNN), the global medical technology business, announces today a review
of 33 published papers that shows fewer wound healing complications in
patients with closed surgical incisions after Negative Pressure Wound Therapy
(NPWT) is applied for three to five days post surgery. The journal Bone and
Joint Research published the review, which was written by an international
panel of experts on NPWT.
"According to a consensus of the randomised studies, there is a strong
argument for the preventative use of NPWT on high-risk, closed surgical
incisions," said Prof. James Stannard, Professor and Orthopaedic Surgeon at
the Missouri Orthopaedic Institute at the University of Missouri, a co-author
of the paper and the first surgeon ever to report the use of NPWT on closed
"Most surgeons are familiar with the efficacy of NPWT on complex open wounds
as that has become a standard of care," said Prof. Stannard. "However, there
is a growing awareness of the potential for incisional NPWT to reduce post
surgical complications in high risk patients and the related costs involved.
We expect that the further development of lower cost, single use NPWT devices
will catalyse additional studies."
The most common surgical site complication is infection. According to the
U.S. Centers for Disease Control and Prevention, about 300,000 surgical site
infections (SSIs) occur every year in the United States, representing 17% of
all healthcare associated infections. SSIs occur in an estimated 5% of
in-patient surgical procedures and result in seven to 10 additional
post-operative hospital days. (Berrios-Torres SI. Surgical Site Infection
(SSI) Toolkit. Activity C: ELC Prevention Collaboratives. U.S. Centers for
Disease Control and Prevention (CDC); 2009. Available here.)
Co-authored by six members of a panel of international experts on NPWT, the
Bone and Joint Research paper examines research from 33 clinical publications
investigating new technologies that can be applied to closed surgical
incisions to help minimise complications. The panel conducted the review in
orthopaedic and other surgical disciplines.
The paper's co-authors are currently completing independent investigator
initiated studies with PICO™, Smith & Nephew's single use NPWT system.
"Single use NPWT devices such as Smith & Nephew's PICO mean that the lower
cost of therapy can create many more opportunities for building clinical
evidence in large randomised studies," said Dr. Robin Martin, a co-author of
the paper and Director of Clinical Sciences at Smith & Nephew. "For a future
article, we plan to assess the evidence for identifying those patients at
greatest risk of surgical site complications in orthopaedic procedures and
review the guidelines to target certain patient groups with NPWT as a
preventive technology. We plan to examine the economic implications for such
an approach as well."
Bone and Joint Research is a UK-based peer reviewed journal that publishes
papers across the entire spectrum of musculoskeletal sciences.
About Smith & Nephew
Smith & Nephew is a global medical technology business dedicated to helping
improve people's lives. With leadership positions in Orthopaedic
Reconstruction, Advanced Wound Management, Sports Medicine and Trauma, Smith &
Nephew has around 11,000 employees and a presence in more than 90 countries.
Annual sales in 2012 were more than $4.1 billion. Smith & Nephew is a member
of the FTSE100 (LSE: SN, NYSE: SNN).
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