Shire Launches Online Educational Resource Center for US Patients with Ulcerative Colitis

    Shire Launches Online Educational Resource Center for US Patients with
                              Ulcerative Colitis

PR Newswire

CHESTERBROOK, Pennsylvania, December 12, 2013

CHESTERBROOK, Pennsylvania, December 12, 2013 /PRNewswire/ --

Patients with ulcerative colitis (UC) can find information, tips and tools to
help manage their disease athttp://www.ShireUCentral.com

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical
company, is pleased to announce the launch of http://www.ShireUCentral.com, an
online disease information and resource center for US patients with ulcerative
colitis. UC is a chronic, life-changing disease in which the inner lining of
all or part of the colon and rectum is inflamed. At Shire UCentral, patients
and their caregivers will find educational information and a variety of
resources to support them along their journey with UC.

"The patient is at the heart of everything we do at Shire, and that includes
Shire UCentral, which was designed with patient needs in mind and to provide
an optimal viewing experience on smart phones, tablets, or desktop computers,"
says Shire Gastrointestinal Business Unit Head Roger Adsett. "Our new online
resource center also reflects Shire's commitment to being a leader in
gastroenterology. It offers a wealth of information for patients suffering
from UC."

Shire UCentral offers the following to patients who are newly diagnosed with
UC, experiencing flares or in remission:

  oUC resources, including an interactive and customizable Doctor Discussion
    Guide to help prepare patients for their next doctor's appointment;
  oTips and advice from medical experts, including the Experts Speak video
    series featuring key opinion experts in the UC therapeutic area;
  oConnections to patient advocacy communities;
  oGeneral information about nutrition and planning a healthy diet;
  oHotline access to an on-call nurse representative who can answer general
    questions about UC, including the incidence, causes and symptoms.

"The Doctor Discussion Guide on Shire UCentral is an excellent tool that can
help patients prepare for more productive interactions with their healthcare
providers," says Dr. Charles Sninsky, MD, a gastroenterologist in Gainesville,
FL. "Patients may help control their UC better when they have open
communications with their doctor."

After December 18, the new on-call nurse representative hotline service,
"Shire UCentral LIVE," will be available Monday through Friday from 8 am to 8
pm ET. Callers may opt-in to receive periodic communications with information
and support about their disease after speaking with a nurse representative.

Laura D. Wingate, Vice President of Patient & Professional Services at the
Crohn's and Colitis Foundation of America, adds, "Patient education and
support are essential components to empowering patients and encouraging shared
decision making. Shire UCentral is another resource for patients with UC and
caregivers in the spectrum of support and information."

To learn more, watch an overview video or visit http://www.ShireUCentral.com

Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs.

We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal,
Internal Medicine and Regenerative Medicine, and we are developing treatments
for symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas.

http://www.shire.com

For further information please contact: Media, Gwen Fisher, 1-484-595-9836

SOURCE Shire plc