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Interim Data to Be Presented for MK-3475, Merck’s Investigational Anti-PD-1 Immunotherapy, in Patients with Advanced Melanoma



  Interim Data to Be Presented for MK-3475, Merck’s Investigational Anti-PD-1
  Immunotherapy, in Patients with Advanced Melanoma

Business Wire

WHITEHOUSE STATION, N.J. -- November 15, 2013

Merck (NYSE: MRK), known as MSD outside the United States and Canada, will
present additional data from patients with advanced melanoma from the Phase IB
trial of MK-3475 on Monday, Nov. 18 at the 10th International Congress of the
Society for Melanoma Research in Philadelphia. MK-3475 is Merck’s
investigational anti-PD-1 immunotherapy. The additional data are from PN001,
an ongoing multi-center, single-arm open-label study evaluating MK-3475
monotherapy in more than 1,000 patients with diverse late-stage cancers
(metastatic carcinoma), predominantly lung and melanoma. The data to be
presented are for patients in the melanoma cohort.

About Merck

Today's Merck is a global healthcare leader working to help the world be well.
Merck is known as MSD outside the United States and Canada. Through our
prescription medicines, vaccines, biologic therapies, and consumer care and
animal health products, we work with customers and operate in more than 140
countries to deliver innovative health solutions. We also demonstrate our
commitment to increasing access to healthcare through far-reaching policies,
programs and partnerships. For more information, visit www.merck.com and
connect with us on Twitter, Facebook and YouTube.

Merck Forward-Looking Statement

This news release includes “forward-looking statements” within the meaning of
the safe harbor provisions of the United States Private Securities Litigation
Reform Act of 1995. These statements are based upon the current beliefs and
expectations of Merck’s management and are subject to significant risks and
uncertainties. There can be no guarantees with respect to pipeline products
that the products will receive the necessary regulatory approvals or that they
will prove to be commercially successful. If underlying assumptions prove
inaccurate or risks or uncertainties materialize, actual results may differ
materially from those set forth in the forward-looking statements.

Risks and uncertainties include but are not limited to, general industry
conditions and competition; general economic factors, including interest rate
and currency exchange rate fluctuations; the impact of pharmaceutical industry
regulation and health care legislation in the United States and
internationally; global trends toward health care cost containment;
technological advances, new products and patents attained by competitors;
challenges inherent in new product development, including obtaining regulatory
approval; Merck’s ability to accurately predict future market conditions;
manufacturing difficulties or delays; financial instability of international
economies and sovereign risk; dependence on the effectiveness of Merck’s
patents and other protections for innovative products; and the exposure to
litigation, including patent litigation, and/or regulatory actions.

Merck undertakes no obligation to publicly update any forward-looking
statement, whether as a result of new information, future events or otherwise.
Additional factors that could cause results to differ materially from those
described in the forward-looking statements can be found in Merck’s 2012
Annual Report on Form 10-K and the company’s other filings with the Securities
and Exchange Commission (SEC) available at the SEC’s Internet site
(www.sec.gov).

Contact:

Merck
Media:
Ian McConnell, 908-423-3046
or
Claire Mulhearn, 908-423-7425
or
Investors:
Carol Ferguson, 908-423-4465
or
Justin Holko, 908-423-5088
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