Cytori Reports Nine Month and Third Quarter 2013 Business and Financial Results Business Wire SAN DIEGO -- November 7, 2013 Cytori Therapeutics (NASDAQ: CYTX) today reports its nine month and third quarter 2013 financial results and provides updates on clinical development, commercialization and corporate development activities. Total revenue for the nine months and quarter ended September 30, 2013 were $8.7 million and $2.7 million, respectively. Net loss for the nine months and quarter ended September 30, 2013 was $16.1 million and $5.3 million, respectively. Milestone Highlights Cytori’s year-to-date accomplishments include the following: *Formed a commercialization partnership for select emerging markets, including $24 million in equity, a long term supply agreement with an initial $7 million product purchase commitment, and up to $500 million in commercial milestones *Under the BARDA contract, the Company made significant progress toward the achievement of critical preclinical milestones needed to seek up to $56 million in additional funding *Expanded the number of actively recruiting centers in the ATHENA clinical trial program to seven and identified additional sites for ATHENA II *Received approvals for the Celution® System in Australia and Singapore *Awarded seven patents, including a methods patent for using adipose-derived regenerative cell therapy for treating renal disease and licensed exclusive rights to a patent related to adipose-derived regenerative cells for the treatment of autoimmune diseases “The recently signed partnership significantly strengthens our balance sheet, accelerates the expansion of our international cardiovascular business, and positions us for future revenue growth,” said Christopher J. Calhoun, Cytori’s Chief Executive Officer. “Year-to-date, we continued to make progress globally in our heart failure program and U.S. trials and are close to achieving all three objectives under the BARDA contract to qualify for the next phase worth up to $56 million.” Financial Performance Total revenues for the first nine months of 2013 were $8.7 million compared to $7.2 million for the first nine months of 2012. Total product and contract revenues for the first nine months of 2013 were $6.9 million, which consisted of $4.4 million in product sales and $2.5 million in contract revenue. Total product and contract revenues for the first nine months of 2012 were $4.8 million, which consisted of $4.7 million in product sales and negligible contract revenues. Total product and cash contract revenues for the third quarter of 2013 were $2.7 million, compared to $1.3 million in the third quarter of 2012. Based on projected sales in the fourth quarter of 2013, Cytori reiterates its 2013 revenue objective of $14 million in combined product and contract revenue. Gross profit for the first nine months and quarter ended September 30, 2013 were $2.1 million and $0.7 million respectively compared to $2.2 million and $0.6 million respectively for the first nine months and quarter ended September 30, 2012. Research and development expenses for the first nine months and quarter ended September 30, 2013 were $12.0 million and $4.1 million compared to $9.6 million and $3.6 million respectively for the first nine months and quarter ended September 30, 2012. The planned increase in research and development expenses is predominately related to reimbursed services performed under the BARDA contract, in addition to increased clinical trial costs. Sales, general and administrative expenses for the first nine months and quarter ended September 30, 2013 were $18.7 million and $6.1 million respectively compared to $18.9 million and $6.2 million respectively for the first nine months and quarter ended September 30, 2012. Net loss for the first nine months of 2013 was $16.1 million, or ($0.24) per share, compared to $28.5 million, or ($0.49) per share, in the first nine months of 2012. Net loss for the third quarter of 2013 was $5.3 million, or ($0.08) per share, compared to $11.2 million, or ($0.19) per share, in the third quarter of 2012. The reduction of net loss for the first nine months of 2013 is predominately attributable to gains totaling $9.3 million from the sale of Puregraft® in the third quarter of 2013 and from the gain on previously held equity interest in the Olympus-Cytori Joint Venture in the second quarter of 2013. Cytori ended the third quarter of 2013 with $10.2 million of cash and cash equivalents and $2.6 million in accounts receivable. Subsequent to the end of the quarter, Cytori entered into a strategic partnership that will bring in $24 million in committed capital before the end of the year from the partnering agreement. The cash is expected to enable the Company to meet potential 2014 milestones such as achieving options under the BARDA contract and presentation of initial ATHENA data. Strategic Partnership Emerging Markets Cytori entered a partnership with Lorem Vascular subsequent to the end of the quarter to commercialize Cytori Cell Therapy in China, Hong Kong, Malaysia, Singapore and Australia. Under the agreement, Cytori and Lorem Vascular entered into a long term supply agreement for a 30-year exclusive license to Cytori Cell Therapy for cardiovascular disease, renal failure, diabetes, and all other indications, except alopecia and aesthetics, in the licensed territories. Pursuant to our agreement, Lorem Vascular will pay up to $500 million in commercial milestones and will initially commit to order $7 million in Celution® devices and consumables. Lorem Vascular will place its first order for $2 million of Cytori Cell Therapy products immediately, followed by a $5 million order to be placed upon regulatory approval in China, anticipated to be received in 2014. In a related transaction, Cytori will receive $24 million in exchange for the sale of 8 million shares of Cytori common stock at $3.00 per share. Equity purchased will be closed in two installments; a $12 million payment has been received and a second $12 million payment that will be made by the end of 2013. In addition, one board seat will be granted to Mr. K.T. Lim, Chairman of Lorem Vascular. Cardiovascular Disease Pipeline Heart Failure: ATHENA I & II Trials ATHENA I is a prospective, multi-center, double-blind, randomized and placebo-controlled clinical trial investigating Cytori Cell Therapy for heart failure due to ischemic heart disease. ATHENA I will enroll 45 patients at a dose of 0.4MM cells/kg at eight centers. During the first quarter of 2014, the Company expects to initiate ATHENA II enrollment of 45 patients at a higher dose of 0.8MM cells/kg at up to ten trial centers. During the recent quarter, Cytori took action to modify the ATHENA protocols to enhance enrollment and safety, streamline the screening process, better align ATHENA I and II trials and facilitate the process of obtaining approval of an anticipated U.S. pivotal trial. Enrollment, which was deferred during the IRB approval process, has now resumed at seven of eight centers. Our updated projection is that ATHENA I should be fully enrolled by April 2014 and the first patient in ATHENA II may be enrolled in January 2014. Presentation of ATHENA I top-line six-month data is expected to be announced in the second half of 2014, full enrollment of ATHENA II is anticipated in the second half of 2014 and initiation of the U.S. pivotal trial in 2015. Acute Myocardial Infarction: ADVANCE Trial ADVANCE is the Company’s European clinical trial for acute myocardial infarction (heart attacks). Cytori previously announced plans to discontinue ADVANCE following a review of the Company’s global cardiovascular strategy, resource utilization and development priorities. The trial has enrolled 23 patients who will continue to be followed according to the trial protocol. BARDA Contract Cytori’s contract with BARDA, a division of the U.S. Department of Health and Human Services, may provide up to $106 million to fully fund the regulatory and clinical trials required by FDA to gain approval for Cytori’s Celution® System for the treatment of thermal burn injuries. The initial phase of the contract includes approximately $5 million in research funding to achieve three principal objectives. Attaining all three objectives qualifies Cytori to seek a second phase of the contract worth up to $56 million in additional funding toward product development and clinical trials. Cytori has submitted a final report demonstrating completion of the first objective, which was validation of the performance of the next-generation Celution® System. During the third quarter, Cytori submitted data to BARDA demonstrating substantial progress on the second and third objectives. On the basis of this progress the Company is in the process of accelerating the scheduling of an In-Process Review (IPR) meeting with BARDA early in the first quarter of 2014. Favorable review at this meeting may lead to funding of up to $32.6 million over three years for Option 1. This would fund a pilot stage clinical trial program in thermal burn injury, ongoing development of the next generation Celution® System, and any FDA-required preclinical studies. Cytori anticipates a second IPR meeting on schedule for Option 3. Option 3 is valued at up to $23.4 million over approximately four years. Commercial Sales Efforts Cytori’s sales efforts continue to focus primarily on researchers performing investigator-initiated and sponsored studies. This supports the Company’s strategy of facilitating the development of additional therapeutic applications for its cell therapy. For the fourth quarter of 2013 and into 2014, product revenue growth will be driven by expanded research and general clinical use based on recent regulatory approvals in Japan, Europe, and Asia Pacific, planned international registration studies, and the aforementioned strategic partnership. Specifically, during the third quarter, Cytori received notice from the Australian Therapeutic Goods Administration (TGA) that the Celution® System was approved for commercial use through inclusion on the Australian Registry of Therapeutic Goods. Additionally, the Celution® System was approved subsequent to the end of the quarter in Singapore and Cytori has registered the Celution® System for commercial sale in New Zealand. Upcoming Milestones Cytori’s key milestones for the next 12 months include the following: *Complete enrollment in the ATHENA I and II trials *Report six-month outcomes from the ATHENA trial *Achieve proof-of-concept milestones in the BARDA contract and qualify Cytori for up to $56 million in additional development funding *Obtain product registration for the Celution® System in China *Achieve product and contract revenue objectives *Publish the long term outcomes from the PRECISE European chronic ischemic heart failure trial Management Conference Call Webcast Cytori will host a management conference call at 5:00 p.m. Eastern Time today to further discuss the Company’s progress. The webcast will be available live and by replay two hours after the call and may be accessed under “Webcasts” in the Investor Relations section of Cytori’s website. If you are unable to access the webcast, you may dial in to the call at +1-877-402-3914, Conference ID: 95080960. About Cytori Cytori Therapeutics is developing cell therapies based on autologous adipose-derived regenerative cells (ADRCs) to treat cardiovascular disease and other medical conditions. Our scientific data suggest ADRCs improve blood flow, moderate the inflammatory response and keep tissue at risk of dying alive. As a result, we believe these cells can be applied across multiple “ischemic” conditions. These therapies are made available to the physician and patient at the point-of-care by Cytori’s proprietary technologies and products, including the Celution® System product family. www.cytori.com Cautionary Statement Regarding Forward-Looking Statements This press release includes forward-looking statements regarding events, trends and business prospects, which may affect our future operating results and financial position, such as our expectation of completion of enrollment of the ATHENA clinical trial by the end of the first quarter of 2014 with six month results in the second half of 2014, full enrollment in ATHENA II in 2014 and initiation of a pivotal trial in 2015, our ability to meet the BARDA proof-of-concept milestones by the first quarter of 2014 and conduct a successful In-Process Review meeting, our expectation of continuing demand from investigator-initiated trial customers, our expectation of product revenue growth based on recent regulatory approvals including Class I registration in Japan, expanded Celution® System CE Mark clearance in Europe for intravascular delivery and tissue ischemia, and approvals and country registrations in other regions throughout the world, our ability to meet our product and contract revenue objectives, our acceleration and expansion of our international cardiovascular business, and our publication of 18-month trial outcomes from the PRECISE trial. Such statements are subject to risks and uncertainties that could cause our actual results and financial position to differ materially. Some of these risks include the level of future interest in our products by Japan research institutions, performance of our Japan distribution network, clinical, pre-clinical and regulatory uncertainties, such as those associated with the ATHENA clinical trial and the BARDA proof-of-concept milestones, including risks in the collection and results of clinical data, final clinical outcomes, dependence on third party performance, performance and acceptance of our products in the marketplace, and other risks and uncertainties described under the "Risk Factors" in our annual and quarterly Securities and Exchange Commission Filings on Forms 10-K and 10-Q. We assume no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made. CYTORI THERAPEUTICS, INC. CONSOLIDATED CONDENSED BALANCE SHEETS (UNAUDITED) As of September As of December 30, 2013 31, 2012 Assets Current assets: Cash and cash equivalents $ 10,205,000 $ 25,717,000 Accounts receivable, net of reserves of $1,218,000 and of $278,000 in 2013 and 2,622,000 3,926,000 2012, respectively Inventories, net 4,138,000 3,175,000 Other current assets 1,128,000 1,161,000 Total current assets 18,093,000 33,979,000 Property and equipment, net of accumulated depreciation of $9,131,000 1,550,000 2,174,000 and of $8,609,000 in 2013 and 2012, respectively Restricted cash and cash equivalents 350,000 350,000 Investment in joint venture — 85,000 Other assets 1,962,000 2,740,000 Intangibles, net 9,345,000 — Goodwill 3,922,000 3,922,000 Total assets $ 35,222,000 $ 43,250,000 Liabilities and Stockholders’ Equity Current liabilities: Accounts payable and accrued expenses $ 5,471,000 $ 7,411,000 Current portion of long-term 1,193,000 9,784,000 obligations, net of discount Termination fee obligation 600,000 — Puregraft divestiture obligation 608,000 — Joint Venture purchase obligation 4,772,000 — Warrant liability — 418,000 Total current liabilities 12,644,000 17,613,000 Deferred revenues, related party — 638,000 Deferred revenues 190,000 2,635,000 Option liability — 2,250,000 Long-term deferred rent and other 754,000 756,000 Long-term obligations, net of discount, 24,822,000 12,903,000 less current portion Total liabilities 38,410,000 36,795,000 Commitments and contingencies Stockholders’ equity: Preferred stock, $0.001 par value; 5,000,000 shares authorized; -0- shares — — issued and outstanding in 2013 and 2012 Common stock, $0.001 par value; 95,000,000 shares authorized; 67,270,466 and 65,914,050 shares issued and 67,000 66,000 outstanding in 2013 and 2012, respectively Additional paid-in capital 287,752,000 281,117,000 Accumulated other comprehensive loss (142,000 ) — Accumulated deficit (290,865,000 ) (274,728,000 ) Total stockholders’ (deficit) equity (3,188,000 ) 6,455,000 Total liabilities and stockholders’ $ 35,222,000 $ 43,250,000 equity CYTORI THERAPEUTICS, INC. CONSOLIDATED CONDENSED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (UNAUDITED) For the Three Months For the Nine Months Ended September 30, Ended September 30, 2013 2012 2013 2012 Product $ 1,616,000 $ 1,314,000 $ 4,416,000 $ 4,741,000 revenues Cost of product 931,000 703,000 2,296,000 2,588,000 revenues Gross profit 685,000 611,000 2,120,000 2,153,000 Development revenues: Development, — — 638,000 2,413,000 related party Development — — 1,179,000 — revenue Government contracts and 1,095,000 2,000 2,503,000 21,000 other 1,095,000 2,000 4,320,000 2,434,000 Operating expenses: Research and 4,123,000 3,555,000 11,992,000 9,615,000 development Sales and 1,786,000 2,450,000 6,453,000 7,406,000 marketing General and 4,332,000 3,777,000 12,225,000 11,489,000 administrative Change in fair value of — 863,000 (418,000 ) 1,244,000 warrant liability Change in fair value of — 300,000 (2,250,000 ) 490,000 option liability Total operating 10,241,000 10,945,000 28,002,000 30,244,000 expenses Operating loss (8,461,000 ) (10,332,000 ) (21,562,000 ) (25,657,000 ) Other income (expense): Loss on asset — — (257,000 ) — disposal Loss on debt — — (708,000 ) — extinguishment Interest 1,000 — 2,000 3,000 income Interest (1,094,000 ) (857,000 ) (2,456,000 ) (2,582,000 ) expense Other income (96,000 ) (17,000 ) (392,000 ) (91,000 ) (expense), net Gain on Puregraft 4,392,000 — 4,392,000 — divestiture Gain on previously held equity — — 4,892,000 — interest in Joint Venture Equity loss from — (42,000 ) (48,000 ) (128,000 ) investment in joint venture Total other income 3,203,000 (916,000 ) 5,425,000 (2,798,000 ) (expense) Net loss $ (5,258,000 ) $ (11,248,000 ) $ (16,137,000 ) $ (28,455,000 ) Other comprehensive income (loss) – foreign (108,000 ) — (142,000 ) — currency translation adjustments Net comprehensive $ (5,366,000 ) $ (11,248,000 ) $ (16,279,000 ) $ (28,455,000 ) loss Basic and diluted net $ (0.08 ) $ (0.19 ) $ (0.24 ) $ (0.49 ) loss per common share Basic and diluted weighted 67,248,384 58,713,036 67,147,584 58,292,911 average common shares CYTORI THERAPEUTICS, INC. CONSOLIDATED CONDENSED STATEMENTS OF CASH FLOWS (UNAUDITED) For the Nine Months Ended September 30, 2013 2012 Cash flows from operating activities: Net loss $ (16,137,000 ) $ (28,455,000 ) Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization 1,169,000 712,000 Amortization of deferred financing 605,000 706,000 costs and debt discount Joint Venture acquisition obligation 204,000 — accretion Provision for doubtful accounts 938,000 99,000 Change in fair value of warrants (418,000 ) 1,244,000 Change in fair value of option (2,250,000 ) 490,000 liabilities Share-based compensation expense 2,723,000 2,907,000 Equity loss from investment in joint 48,000 128,000 venture Loss on asset disposal 257,000 — Gain on previously held equity (4,892,000 ) — interest in Joint Venture Gain on sale of assets (4,392,000 ) — Loss on debt extinguishment 708,000 — Increases (decreases) in cash caused by changes in operating assets and liabilities: Accounts receivable 361,000 698,000 Inventories (975,000 ) (93,000 ) Other current assets 69,000 (253,000 ) Other assets (117,000 ) 16,000 Accounts payable and accrued (1,080,000 ) 254,000 expenses Deferred revenues, related party (638,000 ) (2,413,000 ) Deferred revenues (1,245,000 ) (97,000 ) Long-term deferred rent (2,000 ) 180,000 Net cash used in operating (25,064,000 ) (23,877,000 ) activities Cash flows from investing activities: Purchases of property and equipment (536,000 ) (1,077,000 ) Proceeds from Puregraft divestiture 5,000,000 — License agreement termination fee (600,000 ) — Cash acquired in purchase of Joint 5,000 — Venture Net cash provided by (used in) 3,869,000 (1,077,000 ) investing activities Cash flows from financing activities: Principal payments on long-term (22,292,000 ) (210,000 ) obligations Proceeds from long-term obligations 27,000,000 — Debt issuance costs and loan fees (1,744,000 ) — Payments toward purchase of Joint (141,000 ) — Venture Proceeds from exercise of employee stock options and warrants and stock 147,000 988,000 purchase plan Proceeds from sale of common stock 3,001,000 4,946,000 Costs from sale of common stock (184,000 ) (64,000 ) Net cash provided by financing 5,787,000 5,660,000 activities Effect of exchange rate changes on (104,000 ) — cash and cash equivalents Net decrease in cash and cash (15,512,000 ) (19,294,000 ) equivalents Cash and cash equivalents at 25,717,000 36,922,000 beginning of period Cash and cash equivalents at end of $ 10,205,000 $ 17,628,000 period Contact: Cytori Therapeutics Investor Relations Tom Baker, +1.858.875.5258 email@example.com or Media Megan McCormick, +1.858.875.5279 firstname.lastname@example.org
Cytori Reports Nine Month and Third Quarter 2013 Business and Financial Results
Press spacebar to pause and continue. Press esc to stop.