Through 2022, Growth in the Neuropathic Pain Drug Market Will be Constrained by the Genericization of Sales-Leading Agents from

 Through 2022, Growth in the Neuropathic Pain Drug Market Will be Constrained
    by the Genericization of Sales-Leading Agents from Eli Lilly/Shionogi,
                          Endo/Grunenthal and Pfizer

Neuropathic Back Pain Continues to Account for the Largest Segment of the
Neuropathic Pain Market, According to a New Report from Decision Resources

PR Newswire

BURLINGTON, Mass., Nov. 4, 2013

BURLINGTON, Mass., Nov. 4, 2013 /PRNewswire/ --Decision Resources, one of the
world's leading research and advisory firms for pharmaceutical and healthcare
issues, finds that the loss of U.S. and European market exclusivity of three
sales-leading neuropathic pain (NP) agents—Eli Lilly/Shionogi's
Cymbalta/Xeristar, Endo/Grunenthal's Lidoderm/Versatis and Pfizer's
Lyrica—combined with a lack of transformative emerging therapies forecasted to
launch specifically for NP, will contribute to a slight market decline during
the 2012-2022 study period. Nevertheless, the launch of several high priced,
branded agents that will experience uptake in niche populations within the NP
market will help to counterbalance some of the sales lost to generic erosion.
Consequently, in the United States, France, Germany, Italy, Spain, the United
Kingdom and Japan, combined NP market sales will decrease from $6.3 billion in
2012 to less than $6 billion in 2022.

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The Pharmacor report entitled Neuropathic Pain also reveals that neuropathic
back pain continues to account for the largest segment of the NP market—over
40 percent market share in 2012. Other segments with notable market share
include painful diabetic neuropathy and postsurgical/post-traumatic NP.
Postherpetic neuralgia, neuropathic cancer pain and central NP are among the
more active areas of NP drug development; however, they represented much
smaller segments of the overall NP market in 2012.

The report also finds that one of the greatest unmet needs in NP is a better
understanding of the pathophysiology of the disease. Interviewed thought
leaders note that existing knowledge gaps hamper both current medical practice
and drug development.

"Neuropathic pain has and will continue to be characterized by significant
heterogeneity in its underlying pathophysiological mechanisms, patient
presentation of symptoms and patient responsiveness to therapy," said Decision
Resources Principal Business Insights Analyst Andrea Buurma. "Greater
knowledge of the pathological mechanisms that underlie neuropathic pain could
lead to the identification of better drug targets and ultimately
more-efficacious drug treatments. However, the recent failures of several
promising agents in the late-stage pipeline, that were believed to act on
mechanisms underlying pain, emphasize the challenge of developing drugs for
this indication."

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SOURCE Decision Resources

Contact: Decision Resources Group,Christopher Comfort, 781-993-2597,
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