Affymetrix Axiom® Strawberry Genotyping Array Delivers Automated Analysis for High-Resolution Genome Scanning of Octoploid

  Affymetrix Axiom® Strawberry Genotyping Array Delivers Automated Analysis
  for High-Resolution Genome Scanning of Octoploid Strawberry

Business Wire

SANTA CLARA, Calif. -- October 22, 2013

Affymetrix, Inc. (NASDAQ:AFFX) announces the launch of Axiom Strawberry
Genotyping Array (also called International Strawberry 90K SNP array or
IStraw90), the only solution that successfully enables high-resolution
genotyping and fully automated data analysis of the octoploid strawberry
genome. This 90,000 SNP array will enable complex trait research and set the
stage for multi-trait, marker-assisted breeding of the cultivated garden
strawberry (Fragaria × ananassa).

The cultivated garden strawberry is an allo-octoploid with a chromosome number
of 2n=8x=56. While there are other genotyping technologies available to scan
genomes of agricultural species at high resolution, most have been designed
for diploids. With Affymetrix’ advanced bioinformatics and innovative design
strategy, Axiom Genotyping Solution provides genome-wide genotyping and
accurately calls the genotypes of both diploid and polyploid species. This
technology has already been successfully applied to complex genomes such as
maize, rose, wheat, trout, and salmon.

Axiom Strawberry Genotyping Array was designed through a public-private
partnership between Affymetrix and theInternational RosBREED SNP Consortium
(IRSC), an arm of the "RosBREED" project dedicated to the genetic improvement
of rosaceous crops. The RosBREED team including Genotyping Team Leader Nahla
Bassil (USDA-ARS, Corvallis), Demonstration Breeder Tom Davis (University of
New Hampshire geneticist), and Pedigree-Based Analysis Team Leader Eric van de
Weg (Wageningen University & Research Center) partnered with the Affymetrix
array design and bioinformatics teams to devise SNP selection and data
analysis strategies. RosBREED announced the availability of the array through
its September 2013 newsletter. Preliminary results from the array were
presented at the 2013 annual conference of the American Society for
Horticultural Science.

“IStraw90 gives us the capability to create high-resolution genetic maps of
the strawberry genome and work towards enabling marker-assisted breeding for
strawberry breeders worldwide,” stated Nahla Bassil. “The International
RosBREED SNP consortium has been working towards enabling discovery and
validation of valuable trait loci. IStraw90 will facilitate many of RosBREED’s
goals and expedite marker-assisted breeding in strawberry.”

“The successful design and analysis of the data from the allo-octoploid
strawberry genome was possible only because of the expertise, commitment, and
collaborative efforts of the Axiom myDesign custom array, bioinformatics, and
product support teams within Affymetrix,” stated Eric van de Weg. “It is
awesome to have the tools to construct such high marker-density maps generated
in such a short time. We expect this array to be a valuable resource for
genome-wide analysis and marker-assisted breeding in many American, European
and other breeding programs.”

“Genotyping the octoploid strawberry genome demonstrates the power and
precision of the Axiom Genotyping platform to type genetic variants within
complex genomes,” said Andy Last, Executive Vice President of the Genetic
Analysis Business Unit at Affymetrix. “The array design process and updates to
the automated analysis software used with Axiom Strawberry Genotyping Array
are significant milestones for our platform because they enable the worldwide
plant and animal genotyping community to leverage the Axiom myDesign
customization process and analysis software to genotype even more species of
interest.”

Axiom Strawberry Genotyping Array will complement the catalog of Axiom
Agrigenomics Genotyping Arrays that are available for multiple species,
including bovine, chicken, and buffalo. These products have been used for
genome-wide association studies, quantitative trait locus mapping, genome
mapping, and breeding activities that make use of marker-assisted selection
and genomic selection. As scientists make progress in decoding genomes of
various plants, animals, and fish using next-generation sequencing platforms,
they can advance their research and commercial objectives by translating those
discoveries to routine applications on the Axiom Genotyping platform.

To learn more about Axiom Genotyping Solutions, please visit
www.affymetrix.com/axiom for applications in human diseases research and
www.affymetrix.com/agrigenotyping for applications in agrigenomics.

PLEASE NOTE: Affymetrix, the Affymetrix logo, Axiom, and all other trademarks
are the property of Affymetrix, Inc. All other trademarks are the property of
their respective owners.

Forward-looking statements

All statements in this press release that are not historical are
"forward-looking statements" within the meaning of Section 21E of the
Securities Exchange Act as amended, including statements regarding Affymetrix'
"expectations," "beliefs," "hopes," "intentions," "strategies," or the like.
Such statements are subject to risks and uncertainties that could cause actual
results to differ materially for Affymetrix from those projected. These and
other risk factors are discussed in Affymetrix' Form 10-K for the year ended
December 31, 2012, and other SEC reports for subsequent quarterly periods.

About Affymetrix

Affymetrix technologies enable multiplex and simultaneous analysis of
biological systems at the cell, protein, and gene level, facilitating the
rapid translation of bench-top research into clinical and routine use for
human health and wellness.

We strive to provide leadership and support, partnering with our customers in
pharmaceutical, diagnostic, and biotechnology companies, as well as leading
academic, government, and non-profit research institutes in their quest for
answers toward using biology for a better world.

More than 2,300 microarray systems have been shipped around the world and more
than 48,000 peer-reviewed papers have been published citing our technologies.
Affymetrix is headquartered in Santa Clara, California, and has manufacturing
facilities in Cleveland, Ohio, San Diego, Vienna and Singapore. The Company
has about 1,100 employees worldwide and maintains sales and distribution
operations across Europe, Asia, and Latin America. For more information about
Affymetrix, please visit www.affymetrix.com.

Contact:

Affymetrix, Inc.
Media Contact:
Mindy Lee-Olsen, 408-731-5523
Vice President, Marketing Services
mindy_lee-olsen@affymetrix.com
or
Investor Contact:
Doug Farrell, 408-731-5285
Vice President, Investor Relations
doug_farrell@affymetrix.com
 
Press spacebar to pause and continue. Press esc to stop.