Euretina Presentation "Adoption of JETREA® in My Everyday Practice" Confirms Need for a New Paradigm in Treatment of

 Euretina Presentation "Adoption of JETREA® in My Everyday Practice" Confirms
Need for a New Paradigm in Treatment of Symptomatic VMA/ VMT, Including Those
                           Cases Associated with MH

  PR Newswire

  LEUVEN, Belgium, October 1, 2013

LEUVEN, Belgium, October 1, 2013 /PRNewswire/ --

Largest ever retrospective review of VMA/VMT patients confirms early treatment
  initiation may stop disease progression and lead to better visual function

  *Retrospective review of patients presenting with vitreomacular adhesion
    (VMA), vitreomacular traction (VMT), macular hole (MH) with/ without VMA,
    with or without visual symptoms (n=509)
  *Review period: July 2009 - May 2013, with mean follow up of 2.03 years.
  *VMA is a progressive disease: 16.4% of the eyes diagnosed with VMA
    progressed to VMT within one year.
  *Exact time and/or impact of progression are patient dependent.
  *Spontaneous resolution of VMA occurred in 20% of patients with VMT
  *Early treatment may be required to stop further disease progression and
    improve visual function outcome.

ThromboGenics NV (Euronext Brussels: THR:BR), a biopharmaceutical company
focused on developing and commercializing innovative ophthalmic medicines,
announces that Prof. Dr. Peter Stalmans, Department of Ophthalmology,
University Hospitals Leuven, Belgium, delivered a presentation entitled
"Adoption of JETREA ^® in My Everyday Practice", at the recent EURETINA annual
meeting of European Society of Retina Specialists in Hamburg.

In his presentation, Prof. Stalmans provided details of the largest
retrospective, observational study to date, that looked at his "real world"
experience with patients with vitreomacular adhesion (VMA), vitreomacular
traction (VMT) and macular hole (MH). 

Prof. Stalmans is working at a large, tertiary care ophthalmology center in
Leuven (Belgium). The Leuven center sees 50,000 ambulatory patients every year
and conducts around 2500 intravitreal injections and 7000 surgical procedures
per annum. The retrospective study is leveraging data collected from
electronic medical records gathered at the center between July 2009 and May

During EURETINA, Prof Stalmans also provided insights into his own successful
clinical experience with JETREA ^® when treating patients with early VMT and

Commenting on his presentation Prof. Dr. Peter Stalmans, Department of
Ophthalmology, University Hospitals  Leuven says, " This is the largest
retrospective study conducted using high resolution OCT technology. The data
collected clearly shows that VMA/VMT is a progressive condition and that
spontaneous resolution of VMT is a low occurrence. Based on our findings I
believe that early treatment of these patients may be important if we are to
help them by resolving debilitating symptoms such as metamorphopsia, and
further sight threatening complications such as macular hole. My own
experience of treating patients experiencing metamorphopsia early with 
JETREA ^® has been extremely good with the vast majority of patients
experiencing resolution of their traction. I look forward to treating many
more patients with this novel drug which I believe will play a key role in the
treatment of a wide range of patients with VMT. "

" This new VMA/VMT patient review is the largest ever available, " says Dr.
Patrik De Haes, CEO of ThromboGenics . " For the first time, we are able to
look at  ' real life '  data provided from a tertiary center, " he
continues. " We are pleased to see how the results highlight the opportunity
for JETREA ^® as an early treatment option for those patients who would
normally only be observed. These new data and  ' real life '  insights will
help us to further educate the community about the risk of disease progression
and the patient benefit of early treatment, " he concludes.

A video interview with Prof. Stalmans at Euretina is available at this link:

About ThromboGenics

ThromboGenics is an integrated biopharmaceutical company focused on developing
and commercializing innovative ophthalmic and oncology medicines. The
Company's lead product, JETREA ^® (ocriplasmin), has been approved by the US
FDA for the treatment of symptomatic VMA and was launched in January 2013. 

ThromboGenics signed a strategic partnership with Alcon (Novartis) for the
commercialization of JETREA ^® outside the United States. Under this
agreement, ThromboGenics could receive up to a total of €375 million in
up-front and milestone payments. It will receive significant royalties from
Alcon's net sales of JETREA ^® . ThromboGenics and Alcon intend to share the
costs equally of developing JETREA ^® for a number of new vitreoretinal

In Europe, JETREA ^® is approved for the treatment of vitreomacular traction
(VMT), including when associated with macular hole of diameter less than or
equal to 400 microns. Alcon has launched JETREA ^® in the UK, Germany,
Denmark, Norway, Finland and Sweden. 

ThromboGenics is also further exploring anti-PIGF (Placental Growth Factor),
also referred to as TB-403.

ThromboGenics is headquartered in Leuven, Belgium, and has-offices in Iselin,
NJ (US) and Dublin, Ireland. The Company is listed on the NYSE Euronext
Brussels exchange under the symbol THR. More information is available at .

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking".
Such forward-looking statements are based on current expectations, and,
accordingly, entail and are influenced by various risks and uncertainties. The
Company therefore cannot provide any assurance that such forward-looking
statements will materialize and does not assume an obligation to update or
revise any forward-looking statement, whether as a result of new information,
future events or any other reason. Additional information concerning risks and
uncertainties affecting the business and other factors that could cause actual
results to differ materially from any forward-looking statement is contained
in the Company's Annual Report.

This press release does not constitute an offer or invitation for the sale or
purchase of securities or assets of ThromboGenics in any jurisdiction.  No
securities of ThromboGenics may be offered or sold within the United States
without registration under the U.S. Securities Act of 1933, as amended, or in
compliance with an exemption therefrom, and in accordance with any applicable
U.S. state securities laws.

For further information please contact: ThromboGenics Wouter Piepers, Global
Head of Corporate Communications +32-16-75-13-10 / +32-478-33-56-32 Dr. Patrik De Haes, CEO +32-16-75-13-10 Chris Buyse, CFO +32-16-75-13-10 Citigate Dewe Rogerson David Dible/ Sita Shah
Tel: +44(0)20-7638-9571 The Trout Group (US
investor relations) Todd James/ Simon Harnest Tel: +1-646-378-2926
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