SHIRE PLC: Transaction in Own Shares

Transaction in Own Shares 
August 9, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG) (the "Company") announces
that, in accordance with the authority granted by shareholders at the Company's
Annual General Meeting on April 30, 2013, it purchased 7,521 of its ordinary
shares of 5 pence each ("Ordinary Shares") on August 8, 2013 through both
direct purchases of Ordinary Shares, and through the purchase of Ordinary
Shares underlying ADRs. The highest and lowest price paid for the directly
acquired Ordinary Shares was 2382.00 pence per share and 2375.00 pence per
share respectively, and for those Ordinary Shares acquired though the purchase
of ADRs was 3697.67 cents per share and 3691.00 cents per share respectively. 
The purchased shares will be held as treasury shares. Following the above
purchase, the Company holds 9,614,613 Ordinary Shares as treasury shares and
has 553,252,061 Ordinary Shares in issue (excluding treasury shares). 
The purchases were made by an independent third party which makes its trading
decisions independently of, and uninfluenced by, the Company. The independence
of the third party enables the Company to continue to purchase Ordinary Shares
(including Ordinary Shares underlying ADRs) during close periods and other
prohibited periods, should they arise. The third party has been appointed by
the Company to make purchases to December 31, 2013. 
For further information please contact: 
Investor Relations                                                              
Eric Rojas                         +1 781 482 0999    
Sarah Elton-Farr               +44 1256 894157    
Shire enables people with life-altering conditions to lead better lives. 
Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs. 
We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal,
Internal Medicine and Regenerative Medicine and we are developing treatments
for symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas. 
Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX 
-0- Aug/09/2013 06:00 GMT
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