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SHIRE PLC: Notification of major interests in shares


Notification of major interests in shares

August 5, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG)

1. Identity of the issuer or the underlying issuer of existing shares to Shire which voting rights are attached: plc


                                                                               
                                                                               

2. Reason for the notification State


                                                                          Yes/ 
                                                                           No  

An acquisition or disposal of voting rights Yes

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached No

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

No

An event changing the breakdown of voting rights No

Other (please specify): No

3. Full name of person(s) subject to the notification Legal & General Group obligation: Plc (L&G)


                                                                               
                                                                               
                                                                               
                                                                               

4. Full name of shareholder(s) (if different from 3.): N/A

5. Date of the transaction (and date on which the 01 August 2013 threshold is crossed or reached if different):

6. Date on which issuer notified: 02 August 2013

7. Threshold(s) that is/are crossed or reached: L&G (Below 3%)


                                                                               
    8. Notified details:                                                           

A: Voting rights attached to shares


                                                                               
                                                                               
                                                                               
                           Situation         Resulting situation after the     

previous to triggering Class/type of shares the Triggering transaction if possible using the transaction


      ISIN CODE                                                                
                        Number   Number  Number    Number of      % of voting  
                          of       of      of       voting          rights     
                        Shares   Voting  shares     rights                     
                                 Rights                                        
                                                                               
                                                Direct Indirect Direct Indirect
                                                                               
                                                                               
     JE00B2QKY057         22,269,735                    Below 3%               
                                                                               
                         (As on 14/10/                                         
                             2009)                                             
                                                                               
                                                                               
    

B: Qualifying Financial Instruments                                          
                                                                             
                                                                             

Resulting situation after the triggering transaction


                                                                             
                                                                             
                                                                             

Type of Expiration Exercise/ Number of voting % of

financial date Conversion rights that may be voting instrument Period/ Date acquired if the rights


                                                  instrument                 
                                            is exercised/converted           

N/A N/A N/A N/A N/A


                                                                             
                                                                                

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments


                                                                             
                                                                             

Resulting situation after the triggering transaction


                                                                             
                                                                             

Type of Exercise Expiration Exercise/ Number of % of voting financial price date Conversion voting rights instrument period rights


                                              instrument                     
                                              refers to                      
                                                                             
                                                             Nominal   Delta 
                                                                             
                                                                             

N/A N/A N/A N/A N/A N/A N/A

Total (A+B+C)

Number of voting rights % of voting rights


                                                                             
                 Below 3%                               Below 3%             
                                                                             
    

9. Chain of controlled undertakings through which the voting rights and/or   
the financial instruments are effectively held, if applicable:               

Legal & General Group Plc (Direct and Indirect) (Group)

Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and Indirect)

Legal & General Investment Management Limited (Indirect) (LGIM)

Legal & General Group Plc (Direct) (L&G) (Below 3% = LGAS, LGPL & PMC)

Legal & General Investment Management (Holdings) Legal & General Limited (Direct) (LGIMHD) Insurance Holdings

Limited (Direct) (LGIH)

Legal & General Assurance (Pensions Management) Legal & General Limited (PMC) Assurance Society


                                                      Limited  (LGAS & LGPL) 
                                                                             
                                                      Legal & General        
                                                      Pensions Limited       
                                                      (Direct)  (LGPL)       
                                                                             
    Proxy Voting:                                                                

10. Name of the proxy holder:


                                                                             
                                                                          N/A

11. Number of voting rights proxy holder will cease to hold: N/A

12. Date on which proxy holder will cease to hold voting rights: N/A

13. Additional Notification using the total voting rights figure of information: 553,280,952

14. Contact name: Angela Hayter (LGIM)

15. Contact telephone 020 3124 3851 number:


    Contact at Shire plc: Tony Guthrie, Deputy Company Secretary, 01256 894746

For further information please contact:
    Investor Relations                                                         

Eric Rojas erojas@shire.com +1 781 482 0999

Sarah Elton-Farr seltonfarr@shire.com +44 1256 894157


    

NOTES TO EDITORS
    Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty medicines to meet significant unmet patient needs.

We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal, Internal Medicine and Regenerative Medicine and we are developing treatments for symptomatic conditions treated by specialist physicians in other targeted therapeutic areas.

www.shire.com

END

-0- Aug/05/2013 11:30 GMT

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