SHIRE PLC: Notification of major interests in shares

Notification of major interests in shares 
August 5, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG) 
1. Identity of the issuer or the underlying issuer of existing shares to  Shire
which voting rights are attached:                                          plc  


                                                                               
                                                                               


                                                                           
2. Reason for the notification                                            State 


                                                                          Yes/ 
                                                                           No  


                                                                           
An acquisition or disposal of voting rights                                Yes  
                                                                           
An acquisition or disposal of qualifying financial instruments which may       
result in the acquisition of shares already issued to which voting rights      
are attached                                                               No   
                                                                           
An acquisition or disposal of instruments with similar economic effect to      
qualifying financial instruments                                                
                                                                       No   
                                                                           
An event changing the breakdown of voting rights                           No   
                                                                           
Other (please specify):                                                    No   
                                                                            
3. Full name of person(s) subject to the notification   Legal & General Group  
obligation:                                                   Plc (L&G)         


                                                                               
                                                                               
                                                                               
                                                                               


                                                                           
4. Full name of shareholder(s) (if different from 3.):           N/A            
                                                                           
5. Date of the transaction (and date on which the           01 August 2013     
threshold is crossed                                                           
or reached if different):                                                       
                                                                           
6. Date on which issuer notified:                           02 August 2013      
                                                                           
7. Threshold(s) that is/are crossed or reached:             L&G (Below 3%)      


                                                                               
    8. Notified details:                                                           


                                                                           
A: Voting rights attached to shares                                             


                                                                               
                                                                               
                                                                               
                           Situation         Resulting situation after the     


                      previous to                  triggering              
 Class/type of shares   the Triggering                transaction              
 if possible using the    transaction                                           


      ISIN CODE                                                                
                        Number   Number  Number    Number of      % of voting  
                          of       of      of       voting          rights     
                        Shares   Voting  shares     rights                     
                                 Rights                                        
                                                                               
                                                Direct Indirect Direct Indirect
                                                                               
                                                                               
     JE00B2QKY057         22,269,735                    Below 3%               
                                                                               
                         (As on 14/10/                                         
                             2009)                                             
                                                                               
                                                                               
    

B: Qualifying Financial Instruments                                          
                                                                             
                                                                             


                                                                         
Resulting situation after the triggering transaction                          


                                                                             
                                                                             
                                                                             


Type of     Expiration    Exercise/        Number of voting       % of    
financial       date       Conversion      rights that may be     voting  
  instrument                 Period/ Date      acquired if  the      rights   


                                                  instrument                 
                                            is exercised/converted           


                                                                         
N/A             N/A        N/A              N/A                     N/A       


                                                                             
                                                                                


                                                                         
C: Financial Instruments with similar economic effect to Qualifying Financial
Instruments                                                                   


                                                                             
                                                                             


                                                                         
Resulting situation after the triggering transaction                          


                                                                             
                                                                             


                                                                         
Type of        Exercise Expiration Exercise/  Number of      % of voting     
financial      price    date       Conversion voting         rights          
instrument                         period     rights                          


                                              instrument                     
                                              refers to                      
                                                                             
                                                             Nominal   Delta 
                                                                             
                                                                             


                                                                         
N/A            N/A      N/A        N/A        N/A            N/A      N/A     
                                                                          
Total (A+B+C)                                                                 
                                                                         
Number of voting rights                     % of voting rights                


                                                                             
                 Below 3%                               Below 3%             
                                                                             
    

9. Chain of controlled undertakings through which the voting rights and/or   
the financial instruments are effectively held, if applicable:               


                                                                         
Legal & General Group Plc (Direct and Indirect) (Group)                       
                                                                         
Legal & General Investment Management (Holdings) Limited (LGIMH)             
(Direct and Indirect)                                                         
                                                                         
Legal & General Investment Management Limited (Indirect) (LGIM)               
                                                                          
Legal & General Group Plc (Direct) (L&G) (Below 3% = LGAS, LGPL & PMC)     
                                                                         
Legal & General Investment Management (Holdings)      Legal & General        
Limited (Direct) (LGIMHD)                             Insurance Holdings      
                                                  Limited (Direct) (LGIH) 
                                                                         
Legal & General Assurance (Pensions Management)       Legal & General        
Limited  (PMC)                                        Assurance Society       


                                                      Limited  (LGAS & LGPL) 
                                                                             
                                                      Legal & General        
                                                      Pensions Limited       
                                                      (Direct)  (LGPL)       
                                                                             
    Proxy Voting:                                                                


                                                                         
10. Name of the proxy holder:                                                 


                                                                             
                                                                          N/A


                                                                         
11. Number of voting rights proxy holder will cease to hold:              N/A 
                                                                         
12. Date on which proxy holder will cease to hold voting rights:          N/A 
                                                                          
13. Additional           Notification using the total voting rights figure of
information:                                 553,280,952                      
                                                                         
14. Contact name:        Angela Hayter (LGIM)                                 
                                                                         
15. Contact telephone    020 3124 3851                                       
number:                                                                       
                                                                          


    Contact at Shire plc: Tony Guthrie, Deputy Company Secretary, 01256 894746

For further information please contact:
    Investor Relations                                                         


                                                                       
Eric Rojas                erojas@shire.com            +1 781 482 0999       
                                                                       
Sarah Elton-Farr          seltonfarr@shire.com        +44 1256 894157       
                                                                        


    

NOTES TO EDITORS
    Shire enables people with life-altering conditions to lead better lives.


Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs. 
We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal,
Internal Medicine and Regenerative Medicine and we are developing treatments
for symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas. 
www.shire.com 

END 
-0- Aug/05/2013 11:30 GMT
 
 
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