Over 45 Percent of Surveyed Nephrologists Are Highly Interested in Late-Stage
Chronic Kidney Disease Products from OPKO Health, Fibrogen/Astellas, Keryx and
Akebia, After Reviewing Brief Product Profiles
Following the Voluntary Recall of the ESA Omontys, Surveyed Nephrologists are
Less Likely to Prescribe a New ESA Compared With Descriptions of Other Likely
Future Renal Anemia Products, According to a New Report from BioTrends
EXTON, Pa., July 8, 2013
EXTON, Pa., July 8, 2013 /PRNewswire/ --BioTrends Research Group, one of the
world's leading research and advisory firms for specialized biopharmaceutical
issues, finds that, among surveyed nephrologists, familiarity with the
late-stage nephrology pipeline is low but interest is high for agents that
treat chronic kidney disease. The TreatmentTrends: Nephrology (U.S.) Q2 2013
report finds that more than 45 percent of surveyed nephrologists are highly
interested in OPKO Health's CTAP101, Fibrogen/Astellas Pharmaceuticals'
FG-4592/ASP1517, Keryx Pharmaceuticals' Zerenex (in hemodialysis only) and
Akebia's AKB-6548, after reviewing brief product profiles for each of these
Among six agents in clinical development presented to surveyed nephrologists,
Zerenex, an iron-based phosphate binder, was rated highest in terms of
familiarity, however, 13 percent of nephrologists consider themselves highly
familiar with it.
"The pipeline is filled with agents that, unfortunately, rate low in terms of
surveyed nephrologists' needs for new therapy options," said BioTrends
Research Group Director Rob Dubman. "However, patient lives can be improved
through new treatments that can, for example, lower pills per day or improve
efficacy for phosphate binder treatment, or provide an oral formulation for a
renal anemia treatment."
Over 80 percent of surveyed nephrologists were aware that Affymax/Takeda
Pharmaceuticals' Omontys - an erythropoiesis stimulating agent (ESA) - was
voluntarily recalled in February 2013 due to new postmarketing reports
regarding serious hypersensitivity reactions. More importantly, following this
voluntary recall, surveyed nephrologists indicated that they are significantly
less likely to prescribe a new ESA compared with their likelihood of
prescribing other future renal anemia products based on provided descriptions,
including a new iron product, a new non-ESA product (hypoxia-inducible factor
prolyl-hydroxylase inhibitors), a new ESA with European market experience and
a biosimilar ESA.
TreatmentTrends^®: Nephrology (U.S.) is a syndicated quarterly report series,
based on primary market research that provides a comprehensive view of the
current and expected future management of renal anemia and bone and mineral
metabolism in patients with chronic kidney disease. Topics include the percent
of patients on each therapy, patient share, therapy initiation levels,
perception of current laboratory values, attribute importance and performance
ratings, bundling, compliance, statement agreements and reaction (familiarity,
interest and percentage of patients likely to be candidates) to new products
in development. The Q2 2013 wave published in June 2013 and the Q3 2013 wave
will publish in September 2013.
About BioTrends Research Group
BioTrends Research Group provides syndicated and custom primary market
research to pharmaceutical manufacturers competing in clinically evolving,
specialty pharmaceutical markets. For information on BioTrends publications
and research capabilities, please visit www.bio-trends.com. BioTrends is a
Decision Resources Group company.
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SOURCE BioTrends Research Group
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