Allen Institute for Brain Science Publishes New Data, Expands Open Online Resources

  Allen Institute for Brain Science Publishes New Data, Expands Open Online
  Resources

Business Wire

SEATTLE -- June 13, 2013

The Allen Institute for Brain Science announces its public data release today,
expanding three online resources that advance global progress in neuroscience.
The resources are hosted by the Allen Brain Atlas data portal, which offers
the global research community a unique collection of high-quality neuroscience
datasets and is publicly available at www.brain-map.org.

With this data release, three atlas resources—the Allen Mouse Brain
Connectivity Atlas, Allen Developing Mouse Brain Atlas, and the Allen Mouse
Brain Atlas—have been expanded with new data and additional features.

The Allen Mouse Brain Connectivity Atlas now offers more search and browse
capabilities, as well as a visually stimulating interface to help navigate the
database. An interactive display offers thumbnails with links to 2-D and 3-D
views of detailed anatomy and projection signals, allowing scientists to
explore individual neural connections in the mouse brain for free in a virtual
environment. These data offer scientists a unique look at the
microarchitecture of the mammalian brain, and comprise a critical resource for
understanding how each of over a hundred million neurons is interconnected.
The Atlas will help scientists identify the neural circuits governing behavior
and other brain functions, examine how such circuits are formed in
development, and advance understanding of a variety of disorders and diseases
involving the brain. The Allen Mouse Brain Connectivity Atlas was first
released in November 2011 and has been expanded regularly since that time; it
now contains detailed projection mapping data from ~200 brain regions.

Another resource, the Allen Developing Mouse Brain Atlas has been
significantly updated with new features. Since its first release in 2010 this
Atlas has provided scientists a database of information to understand the
changing patterns of gene expression throughout development. Today, the Atlas
has been expanded with an updated reference atlas, offering an interactive
platform to search brain anatomy at different stages of development. Further,
the data release today adds new search functions that will allow researchers
to more easily scan large quantities of data, as well as search for
correlations in gene expression among different stages of development.

The Allen Mouse Brain Atlas, the Allen Institute’s flagship Atlas product
which first appeared in 2004 has also been updated to include data from the
Institute’s Sleep Study and Mouse Diversity Study. All of this data is now
viewable in the Brain Explorer® software, a 3-D visualization tool that
provides anatomical context for viewing gene expression throughout the brain.

About the Allen Brain Atlas resources

The Allen Brain Atlas resources, created by the Allen Institute for Brain
Science as open online public resources, integrate large-scale, systematically
generated gene expression and anatomic datasets, complete with powerful search
and viewing tools. Each month, the Allen Brain Atlas resources receive
approximately 50,000 visits from researchers worldwide. Regular updates and
data releases put an increasing amount of valuable data and powerful search
and viewing tools in the hands of scientists and research organizations
everywhere, thereby accelerating understanding of the brain and related
disorders and diseases. The Allen Institute’s next public data release is
scheduled for October 2013.

About the Allen Institute for Brain Science

The Allen Institute for Brain Science (www.alleninstitute.org) is an
independent, 501(c)(3) nonprofit medical research organization dedicated to
accelerating the understanding of how the human brain works in health and
disease. Using a big science approach, the Allen Institute generates useful
public resources used by researchers and organizations around the globe,
drives technological and analytical advances, and discovers fundamental brain
properties through integration of experiments, modeling and theory. Launched
in 2003 with a seed contribution from founder and philanthropist Paul G.
Allen, the Allen Institute is supported by a diversity of government,
foundation and private funds to enable its projects. Given the Institute’s
achievements, Mr. Allen committed an additional $300 million in 2012 for the
first four years of a ten-year plan to further propel and expand the
Institute’s scientific programs, bringing his total commitment to date to $500
million. The Allen Institute’s data and tools are publicly available online at
www.brain-map.org.

Contact:

Edelman for the Allen Institute for Brain Science
Steven Cooper, 646-358-2765
press@alleninstitute.org