SAP and Technical University Munich Decode Human Proteome and Make Data Available for Biomedical Research

   SAP and Technical University Munich Decode Human Proteome and Make Data
                      Available for Biomedical Research

SAP and the Technical University of Munich (TUM) Decode and Analyze Human
Proteome in ProteomicsDB With the Help of SAP HANA®

PR Newswire

WALLDORF, Germany, June 11, 2013

WALLDORF, Germany, June 11, 2013 /PRNewswire/ --SAP AG (NYSE: SAP) and
Technical University Munich (TUM) today announced ProteomicsDB, a new offering
based on the SAP HANA® platform that stores protein and peptide
identifications from mass spectrometry-based experiments. The proteomic data
assembled in the new offering resulted in the identification of proteins
mapping to over 18,000 human genes. This represents 90 percent coverage of the
human proteome. Data stored and analyzed within ProteomicsDB can be used in
basic and biomedical research for discovering therapeutic targets and
developing new drugs as well as enhanced diagnosis methods.

(Logo: http://photos.prnewswire.com/prnh/20110126/AQ34470LOGO)

As personalized medicine is on the rise, the healthcare field is discovering
the opportunities of big data analysis. The result of a joint project between
the TUM Chair of Proteomics and Bioanalytics, SAP and the SAP Innovation
Center, ProteomicsDB is a major step forward in human proteomics. It currently
contains more than 11,000 datasets from human cancer cell lines, tissues and
body fluids and enables real-time analysis of this highly dimensional data and
creates instant value by allowing to test analytical hypothesis.

ProteomicsDB is based on the SAP HANA for rapid data mining and visualization.
It has been built to enable public sharing of mass spectrometry-based
proteomic datasets as well as to allow users to access and review data prior
to publication. The database is backed with 50 TB of storage, 2 TB RAM and 160
processing units. A direct interface to the programming languages L, C++ and R
allows more flexible calculations than are possible with standard SQL. The Web
interface is built on a JavaScript framework for HTML5 and optimized for
Google Chrome but also available under Internet Explorer and Mozilla Firefox.
An easy-to-use and fast Web interface allows users to browse and upload data
to the repository as well as browsing the human proteome, including protein
level information such as protein functionand expression.

ProteomicsDB will be available free of charge. The database will be a valuable
asset for researchers in the field of life sciences as well as for the
pharmaceutical and biotechnology industry. Insights from analyzing the
inherent datasets can be used in biomedical research and for example in
developing new drugs that operate in a more targeted way without adversely
influencing other cellular processes, helping to reduce side effects.

"The vast amounts of molecular data generated in biomedical research
increasingly challenge the ability of scientists to see 'the forest for the
trees," said Prof. Dr. Bernhard Kuster of TUM. "ProteomicsDB is a significant
step ahead in our research aiming at a better understanding of human disease
and more informed future treatments. The software helps us and others to
store, integrate and analyze experimental data in real time, allowing us to
study more complex biological systems at greater depth than previously
possible."

For more information, visit the SAP Newsroom.

About TUM

Technische Universitat Munchen (TUM) is one of Europe's leading universities.
It has roughly 500 professors, 9,000 academic and non-academic staff, and
32,000 students. It focuses on the engineering sciences, natural sciences,
life sciences, medicine, and economic sciences. After winning numerous awards,
it was selected as an "Excellence University" in 2006 and 2012 by the Science
Council (Wissenschaftsrat) and the German Research Foundation (DFG). In both
international and national rankings, TUM is rated as one of Germany's top
universities and is dedicated to the ideal of a top-level research-oriented
entrepreneurial university. The university's global presence includes offices
in Beijing (China), Brussels (Belgium), Cairo (Egypt), Mumbai (India) and Sao
Paulo (Brazil). The German Institute of Science and Technology (GIST - TUM
Asia), founded in 2002 in Singapore, is the first research campus of a German
university abroad. www.tum.de

About SAP

As market leader in enterprise application software, SAP (NYSE: SAP) helps
companies of all sizes and industries run better. From back office to
boardroom, warehouse to storefront, desktop to mobile device – SAP empowers
people and organizations to work together more efficiently and use business
insight more effectively to stay ahead of the competition. SAP applications
and services enable more than 238,000 customers to operate profitably, adapt
continuously, and grow sustainably. For more information, visit www.sap.com.

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For more information, press only:
Cathrin von Osten, +49 (6227) 7-63908, cathrin.von.osten@sap.com, CET
Samantha Finnegan, +1 (650) 276-9350, samantha.finnegan@sap.com, PDT
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TUM Corporate Communications Center, +49 (89) 289-22778, CET, presse@tum.de

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