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TRADE NEWS: Agilent Technologies to Host Forensics Webinar on LC/MS/MS Methods for Cannabinoid, Benzodiazepine Analysis

  TRADE NEWS: Agilent Technologies to Host Forensics Webinar on LC/MS/MS
  Methods for Cannabinoid, Benzodiazepine Analysis

Business Wire

SANTA CLARA, Calif. -- June 4, 2013

Agilent Technologies Inc. (NYSE: A) today announced it will host a forensics
webinar on Thursday, June 20, focusing on liquid chromatography/tandem mass
spectrometry methods for cannabinoid and benzodiazepine quantitation in whole
blood samples.

The new quantitative methods, designed to run on Agilent’s LC/MS/MS
instrumentation, fulfill stringent validation guidelines and provide forensic
toxicology laboratories with a complete protocol for the quantitation of two
of the most commonly abused drug classes in the United States. This set of
Agilent methods is the first in a series now under evaluation by the Virginia
Department of Forensic Science. Additional methods will cover 150 commonly
abused drugs, spanning more than 10 classes of drugs, including designer
drugs, for use in forensic toxicology.

During the webinar, Dr. Rebecca Wagner, research analyst from Virginia’s
Department of Forensic Science, will describe the methods and their
applications in detail. Attendees will receive electronic access to the
complete set of standard operating procedures, detailed validation data, and
the LC/MS/MS method to help their laboratories implement the methodology. The
webinar will also be available for on-demand replay.

“One of the greatest challenges laboratories face when onboarding new
technology is method development and validation,” said Tom Gluodenis,
Agilent’s global marketing manager of forensics and toxicology. “That’s why we
have collaborated with lab director Linda Jackson and her team at the Virginia
Department of Forensic Science to develop a set of standardized LC/MS/MS
methods for law enforcement’s most commonly tested drugs. This set of panels
will enable forensic toxicology laboratories to obtain immediate, high-quality
results with minimal effort.”

“We have developed two separate quantitative methods for the analysis of
cannabinoids, benzodiazepines and their metabolites,” said Dr. Wagner. “These
standardized methods meet rigorous validation guidelines, including those
proposed by the Scientific Working Group for Forensic Toxicology. They take
the onus off toxicologists to develop their own quantitative methods, and
provide them with thoroughly validated methods for some of their most commonly
analyzed compounds.”

“Now, when laboratories purchase Agilent LC/MS/MS instrumentation,” Gluodenis
said, “we can provide them with both highly reliable technology and a set of
advanced screening solutions that have been validated by one of the nation’s
preeminent forensic institutions.”

Method Development

The Virginia Department of Forensic Science analyzes biological specimens for
the presence or absence of drugs and alcohol in DUI/DUID, medical examiner,
and police cases. Cannabinoids and benzodiazepines are two of the more
frequently quantitated drug classes for DUID cases in the Commonwealth of
Virginia. In 2012, 2,524 DUID cases were analyzed. Of those cases, 35 percent
contained cannabinoids and 31 percent contained benzodiazepines.

Two separate quantitative methods have been developed and validated that
include, but are not limited to, the experiments described in the
method-validation guidelines proposed by the Scientific Working Group for
Forensic Toxicology. The cannabinoid method targets were THC, THC-COOH,
THC-OH, cannabinol and cannabidiol. There were 22 target compounds for the
benzodiazepine method that included parent compounds and their metabolites.
The department’s validation procedures, in conjunction with the proposed
SWGTOX guidelines, have facilitated the implementation of a standard method
development and validation plan. In the live webinar presentation on June 20,
the methods will be described in detail, from initial development to
implementation in the four laboratories that comprise the Virginia Department
of Forensic Science.

To register for the webinar, “LC/MS/MS Validation of a Cannabinoid and
Benzodiazepine Method with Comparison to the Proposed SWGTOX Method Validation
Standards,” visit RTI International’s Forensic Science Education website.

About the Virginia Department of Forensic Science

The Virginia Department of Forensic Science is a nationally accredited
forensic laboratory system serving all state and local law enforcement
agencies, medical examiners and commonwealth attorneys in Virginia. Examiners
provide technical assistance, training, evidence evaluation and analysis, and
provide expert testimony related to the full spectrum of physical evidence
recovered from crime scenes.

About the Scientific Working Group for Forensic Toxicology

The Scientific Working Group for Forensic Toxicology develops and disseminates
consensus professional standards for the practice of forensic toxicology and
establishes protocols for forensic toxicologists, including quality assurance
and quality control, education and training, accreditation and certification.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is the world’s premier measurement company
and a technology leader in chemical analysis, life sciences, diagnostics,
electronics and communications. The company’s 20,500 employees serve customers
in more than 100 countries. Agilent had revenues of $6.9 billion in fiscal
2012. Information about Agilent is available at www.agilent.com.

NOTE TO EDITORS: Further technology, corporate citizenship and executive news
is available at www.agilent.com/go/news.

Contact:

Agilent Technologies Inc.
Susan Berg, +1 408-553-7093
susan_berg1@agilent.com