SHIRE PLC: Block Listing Six Monthly Return

BLOCK LISTING SIX MONTHLY RETURN 
May 23, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG) 
Name of applicant:                     Shire plc                                
                                                                           
Name of scheme:                        2000 Executive Share Option Scheme       
                                                                           
Period of return:            From:     November 23,     To:   May 22, 2013      
                                   2012                                     
                                                                           
Balance of unallotted securities under 3,476,451                               
scheme(s) from previous return:                                                 
                                                                           
Plus: The amount by which the block    Nil                                     
scheme(s) has been increased since the                                         
date of the last return (if any                                                
increase has been applied for):                                                 
                                                                           
Less: Number of securities issued/     29,569                                  
allotted under scheme(s) during period                                         
(see LR3.5.7G):                                                                 
                                                                           
Equals: Balance under scheme(s) not    3,446,882                               
yet issued/allotted at end of period:                                           
Name of applicant:                     Shire plc                                
                                                                           
Name of scheme:                        Shire Sharesave Scheme                   
                                                                           
Period of return:            From:     November 23,     To:   May 22, 2013      
                                   2012                                     
                                                                           
Balance of unallotted securities under 115,392                                 
scheme(s) from previous return:                                                 
                                                                           
Plus: The amount by which the block    95,000                                  
scheme(s) has been increased since the                                         
date of the last return (if any                                                
increase has been applied for):                                                 
                                                                           
Less: Number of securities issued/     Nil                                     
allotted under scheme(s) during period                                         
(see LR3.5.7G):                                                                 
                                                                           
Equals: Balance under scheme(s) not    210,392                                 
yet issued/allotted at end of period:                                           
Name of applicant:                     Shire plc                                
                                                                           
Name of scheme:                        Portfolio Share Plan                     
                                                                           
Period of return:            From:     November 23,     To:   May 22, 2013      
                                   2012                                     
                                                                           
Balance of unallotted securities under 2,664,097                               
scheme(s) from previous return:                                                 
                                                                           
Plus: The amount by which the block    Nil                                     
scheme(s) has been increased since the                                         
date of the last return (if any                                                
increase has been applied for):                                                 
                                                                           
Less: Number of securities issued/     263,117                                 
allotted under scheme(s) during period                                         
(see LR3.5.7G):                                                                 
                                                                           
Equals: Balance under scheme(s) not    2,400,980                               
yet issued/allotted at end of period:                                           
Name of applicant:                     Shire plc                                
                                                                           
Name of scheme:                        Employee Stock Purchase Plan             
                                                                           
Period of return:            From:     March 6, 2013    To:   May 22, 2013      
                                                                           
Balance of unallotted securities under Nil                                     
scheme(s) from previous return:                                                 
                                                                           
Plus: The amount by which the block    90,000                                  
scheme(s) has been increased since the                                         
date of the last return (if any                                                
increase has been applied for):                                                 
                                                                           
Less: Number of securities issued/     Nil                                     
allotted under scheme(s) during period                                         
(see LR3.5.7G):                                                                 
                                                                           
Equals: Balance under scheme(s) not    90,000                                  
yet issued/allotted at end of period:                                           
Name of contact:                        Tony Guthrie, Deputy Company Secretary  
                                                                           
Address of contact:                     Hampshire International Business Park   


                                                                               
                                        Basingstoke, Hampshire, RG24 8EP       


                                                                           
Telephone number of contact:            01256 894746                            
For further information please contact: 
Investor Relations                                                              
                                                                           
Eric Rojas                              erojas@shire.com     +1 781 482 0999    
                                                                           
Sarah Elton-Farr                        seltonfarr@shire.com +44 1256 894157    
NOTES TO EDITORS 
Shire enables people with life-altering conditions to lead better lives. 
Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs. 
We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal,
Internal Medicine and Regenerative Medicine and we are developing treatments
for symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas. 
www.shire.com 
                                                                
Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX 
Press Release                                      
                                              
www.shire.com                                      
END 
-0- May/23/2013 14:30 GMT
 
 
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